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Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment.
Izreig S, Gariepy A, Kaymak I, Bridges HR, Donayo AO, Bridon G, DeCamp LM, Kitchen-Goosen SM, Avizonis D, Sheldon RD, Laister RC, Minden MD, Johnson NA, Duchaine TF, Rudoltz MS, Yoo S, Pollak MN, Williams KS, Jones RG. Izreig S, et al. Among authors: jones rg. Cell Rep Med. 2020 May 19;1(2):100014. doi: 10.1016/j.xcrm.2020.100014. Cell Rep Med. 2020. PMID: 32478334 Free PMC article.
AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo.
Faubert B, Boily G, Izreig S, Griss T, Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, Mamer OA, Avizonis D, DeBerardinis RJ, Siegel PM, Jones RG. Faubert B, et al. Among authors: jones rg. Cell Metab. 2013 Jan 8;17(1):113-24. doi: 10.1016/j.cmet.2012.12.001. Epub 2012 Dec 27. Cell Metab. 2013. PMID: 23274086 Free PMC article.
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.
Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo AR, Kool M, Agnihotri S, El-Naggar A, Yu B, Somasekharan SP, Faubert B, Bridon G, Tognon CE, Mathers J, Thomas R, Li A, Barokas A, Kwok B, Bowden M, Smith S, Wu X, Korshunov A, Hielscher T, Northcott PA, Galpin JD, Ahern CA, Wang Y, McCabe MG, Collins VP, Jones RG, Pollak M, Delattre O, Gleave ME, Jan E, Pfister SM, Proud CG, Derry WB, Taylor MD, Sorensen PH. Leprivier G, et al. Among authors: jones rg. Cell. 2013 May 23;153(5):1064-79. doi: 10.1016/j.cell.2013.04.055. Cell. 2013. PMID: 23706743 Free PMC article.
PGC-1α supports glutamine metabolism in breast cancer.
McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. McGuirk S, et al. Among authors: jones rg. Cancer Metab. 2013 Dec 5;1(1):22. doi: 10.1186/2049-3002-1-22. Cancer Metab. 2013. PMID: 24304688 Free PMC article.
Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.
Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Wynosky-Dolfi MA, et al. Among authors: jones rg. J Exp Med. 2014 Apr 7;211(4):653-68. doi: 10.1084/jem.20130627. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638169 Free PMC article.
PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer.
Dupuy F, Tabariès S, Andrzejewski S, Dong Z, Blagih J, Annis MG, Omeroglu A, Gao D, Leung S, Amir E, Clemons M, Aguilar-Mahecha A, Basik M, Vincent EE, St-Pierre J, Jones RG, Siegel PM. Dupuy F, et al. Among authors: jones rg. Cell Metab. 2015 Oct 6;22(4):577-89. doi: 10.1016/j.cmet.2015.08.007. Epub 2015 Sep 10. Cell Metab. 2015. PMID: 26365179 Free article.
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Vincent EE, Sergushichev A, Griss T, Gingras MC, Samborska B, Ntimbane T, Coelho PP, Blagih J, Raissi TC, Choinière L, Bridon G, Loginicheva E, Flynn BR, Thomas EC, Tavaré JM, Avizonis D, Pause A, Elder DJ, Artyomov MN, Jones RG. Vincent EE, et al. Among authors: jones rg. Mol Cell. 2015 Oct 15;60(2):195-207. doi: 10.1016/j.molcel.2015.08.013. Mol Cell. 2015. PMID: 26474064 Free article.
411 results