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DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse.
Zhou W, Hinoue T, Barnes B, Mitchell O, Iqbal W, Lee SM, Foy KK, Lee KH, Moyer EJ, VanderArk A, Koeman JM, Ding W, Kalkat M, Spix NJ, Eagleson B, Pospisilik JA, Szabó PE, Bartolomei MS, Vander Schaaf NA, Kang L, Wiseman AK, Jones PA, Krawczyk CM, Adams M, Porecha R, Chen BH, Shen H, Laird PW. Zhou W, et al. Among authors: jones pa. Cell Genom. 2022 Jul 13;2(7):100144. doi: 10.1016/j.xgen.2022.100144. Cell Genom. 2022. PMID: 35873672 Free PMC article.
Cancer epigenetics comes of age.
Jones PA, Laird PW. Jones PA, et al. Nat Genet. 1999 Feb;21(2):163-7. doi: 10.1038/5947. Nat Genet. 1999. PMID: 9988266 Review.
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW. Weisenberger DJ, et al. Among authors: jones pa. Nucleic Acids Res. 2008 Aug;36(14):4689-98. doi: 10.1093/nar/gkn455. Epub 2008 Jul 15. Nucleic Acids Res. 2008. PMID: 18628296 Free PMC article.
Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.
Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, Koh CJ. Choi IS, et al. Among authors: jones pa. Urology. 2013 Jul;82(1):253.e9-15. doi: 10.1016/j.urology.2013.04.010. Urology. 2013. PMID: 23806407 Free PMC article.
Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine.
Liu M, Ohtani H, Zhou W, Ørskov AD, Charlet J, Zhang YW, Shen H, Baylin SB, Liang G, Grønbæk K, Jones PA. Liu M, et al. Among authors: jones pa. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10238-44. doi: 10.1073/pnas.1612262113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573823 Free PMC article.
Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand up 2 cancer study.
Azad NS, El-Khoueiry A, Yin J, Oberg AL, Flynn P, Adkins D, Sharma A, Weisenberger DJ, Brown T, Medvari P, Jones PA, Easwaran H, Kamel I, Bahary N, Kim G, Picus J, Pitot HC, Erlichman C, Donehower R, Shen H, Laird PW, Piekarz R, Baylin S, Ahuja N. Azad NS, et al. Among authors: jones pa. Oncotarget. 2017 May 23;8(21):35326-35338. doi: 10.18632/oncotarget.15108. Oncotarget. 2017. PMID: 28186961 Free PMC article. Clinical Trial.
DNA methylation enables transposable element-driven genome expansion.
Zhou W, Liang G, Molloy PL, Jones PA. Zhou W, et al. Among authors: jones pa. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19359-19366. doi: 10.1073/pnas.1921719117. Epub 2020 Jul 27. Proc Natl Acad Sci U S A. 2020. PMID: 32719115 Free PMC article.
702 results