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Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI, Tuveson DA, Fearon DT. Feig C, et al. Among authors: jones jo. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7. doi: 10.1073/pnas.1320318110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277834 Free PMC article.
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.
Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, Kraman M, McKenna B, Wells RJ, Zhao Q, Caballero OL, Larder R, Coll AP, O'Rahilly S, Brindle KM, Teichmann SA, Tuveson DA, Fearon DT. Roberts EW, et al. Among authors: jones jo. J Exp Med. 2013 Jun 3;210(6):1137-51. doi: 10.1084/jem.20122344. Epub 2013 May 27. J Exp Med. 2013. PMID: 23712428 Free PMC article.
TOX3 mutations in breast cancer.
Jones JO, Chin SF, Wong-Taylor LA, Leaford D, Ponder BA, Caldas C, Maia AT. Jones JO, et al. PLoS One. 2013 Sep 19;8(9):e74102. doi: 10.1371/journal.pone.0074102. eCollection 2013. PLoS One. 2013. PMID: 24069272 Free PMC article.
A purine metabolic checkpoint that prevents autoimmunity and autoinflammation.
Saveljeva S, Sewell GW, Ramshorn K, Cader MZ, West JA, Clare S, Haag LM, de Almeida Rodrigues RP, Unger LW, Iglesias-Romero AB, Holland LM, Bourges C, Md-Ibrahim MN, Jones JO, Blumberg RS, Lee JC, Kaneider NC, Lawley TD, Bradley A, Dougan G, Kaser A. Saveljeva S, et al. Among authors: jones jo. Cell Metab. 2022 Jan 4;34(1):106-124.e10. doi: 10.1016/j.cmet.2021.12.009. Cell Metab. 2022. PMID: 34986329 Free PMC article.
102 results