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Poly(D,l-lactide-co-glycolide) particles are metabolised by the gut microbiome and elevate short chain fatty acids.
McCoubrey LE, Ferraro F, Seegobin N, Verin J, Alfassam HA, Awad A, Marzorati M, Verstrepen L, Ghyselinck J, De Munck J, De Medts J, Steppe E, De Vleeschhauwer V, De Rocker G, Droesbeke A, De Rijck M, Vanthoor S, Moens F, Siepmann J, Siepmann F, Gaisford S, Orlu M, Basit AW. McCoubrey LE, et al. Among authors: ghyselinck j. J Control Release. 2024 Mar 26;369:163-178. doi: 10.1016/j.jconrel.2024.03.039. Online ahead of print. J Control Release. 2024. PMID: 38521168 Free article.
Capacity of a Microbial Synbiotic To Rescue the In Vitro Metabolic Activity of the Gut Microbiome following Perturbation with Alcohol or Antibiotics.
Tierney BT, Van den Abbeele P, Al-Ghalith GA, Verstrepen L, Ghyselinck J, Calatayud M, Marzorati M, Gadir AA, Daisley B, Reid G, Bron PA, Gevers D, Dhir R, Simmons SL. Tierney BT, et al. Among authors: ghyselinck j. Appl Environ Microbiol. 2023 Mar 29;89(3):e0188022. doi: 10.1128/aem.01880-22. Epub 2023 Feb 22. Appl Environ Microbiol. 2023. PMID: 36840551 Free PMC article.
The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue™ Cell Co-Culture Model.
Liu L, Lu Y, Xu C, Chen H, Wang X, Wang Y, Cai B, Li B, Verstrepen L, Ghyselinck J, Marzorati M, Yao Q. Liu L, et al. Among authors: ghyselinck j. Front Pharmacol. 2022 Mar 15;13:820543. doi: 10.3389/fphar.2022.820543. eCollection 2022. Front Pharmacol. 2022. PMID: 35370677 Free PMC article.
Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease.
Ghyselinck J, Verstrepen L, Moens F, Van Den Abbeele P, Bruggeman A, Said J, Smith B, Barker LA, Jordan C, Leta V, Chaudhuri KR, Basit AW, Gaisford S. Ghyselinck J, et al. Int J Pharm X. 2021 Jul 2;3:100087. doi: 10.1016/j.ijpx.2021.100087. eCollection 2021 Dec. Int J Pharm X. 2021. PMID: 34977556 Free PMC article.
Microbial fermentation of Fossence™, a short-chain fructo-oligosaccharide, under simulated human proximal colonic condition and assessment of its prebiotic effects-a pilot study.
Tiwari DP, Shah P, Van den Abbeele P, Marzorati M, Calatayud M, Ghyselinck J, Dubey AK, Narayanan S, Jain M. Tiwari DP, et al. Among authors: ghyselinck j. FEMS Microbiol Lett. 2021 Dec 17;368(21-24):fnab147. doi: 10.1093/femsle/fnab147. FEMS Microbiol Lett. 2021. PMID: 34849765
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