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2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA.
Pantic B, Ives D, Mennuni M, Perez-Rodriguez D, Fernandez-Pelayo U, Lopez de Arbina A, Muñoz-Oreja M, Villar-Fernandez M, Dang TJ, Vergani L, Johnston IG, Pitceathly RDS, McFarland R, Hanna MG, Taylor RW, Holt IJ, Spinazzola A. Pantic B, et al. Among authors: johnston ig. Nat Commun. 2021 Dec 6;12(1):6997. doi: 10.1038/s41467-021-26829-0. Nat Commun. 2021. PMID: 34873176 Free PMC article.
Mitochondrial Network State Scales mtDNA Genetic Dynamics.
Aryaman J, Bowles C, Jones NS, Johnston IG. Aryaman J, et al. Among authors: johnston ig. Genetics. 2019 Aug;212(4):1429-1443. doi: 10.1534/genetics.119.302423. Epub 2019 Jun 28. Genetics. 2019. PMID: 31253641 Free PMC article.
Evolving mtDNA populations within cells.
Johnston IG, Burgstaller JP. Johnston IG, et al. Biochem Soc Trans. 2019 Oct 31;47(5):1367-1382. doi: 10.1042/BST20190238. Biochem Soc Trans. 2019. PMID: 31484687 Free PMC article. Review.
Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.
Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hämäläinen RH, Pellico J, Justo-Méndez R, Fernández-Toro JM, Clavería C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruíz-Cabello J, Enríquez JA. Latorre-Pellicer A, et al. Among authors: johnston ig. Cell Metab. 2019 Dec 3;30(6):1120-1130.e5. doi: 10.1016/j.cmet.2019.09.007. Epub 2019 Oct 3. Cell Metab. 2019. PMID: 31588014 Free PMC article.
107 results