Johnston GAR - Search Results

1

Targeting GABA_C Receptors Improves Post-Stroke Motor Recovery.

van Nieuwenhuijzen PS, Parker K, Liao V, Houlton J, Kim HL, Johnston GAR, Hanrahan JR, Chebib M, Clarkson AN. van Nieuwenhuijzen PS, et al. Among authors: johnston gar. Brain Sci. 2021 Mar 2;11(3):315. doi: 10.3390/brainsci11030315. Brain Sci. 2021. PMID: 33801560 Free PMC article.

2

Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors.

Hall BJ, Chebib M, Hanrahan JR, Johnston GA. Hall BJ, et al. Eur J Pharmacol. 2004 Apr 26;491(1):1-8. doi: 10.1016/j.ejphar.2004.03.014. Eur J Pharmacol. 2004. PMID: 15102527

3

Novel gamma-aminobutyric acid rho1 receptor antagonists; synthesis, pharmacological activity and structure-activity relationships.

Kumar RJ, Chebib M, Hibbs DE, Kim HL, Johnston GA, Salam NK, Hanrahan JR. Kumar RJ, et al. J Med Chem. 2008 Jul 10;51(13):3825-40. doi: 10.1021/jm7015842. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18528996

4

Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice.

Fernandez SP, Mewett KN, Hanrahan JR, Chebib M, Johnston GA. Fernandez SP, et al. Neuropharmacology. 2008 Oct;55(5):900-7. doi: 10.1016/j.neuropharm.2008.06.069. Epub 2008 Jul 9. Neuropharmacology. 2008. PMID: 18657554

5

Novel, potent, and selective GABAC antagonists inhibit myopia development and facilitate learning and memory.

Chebib M, Hinton T, Schmid KL, Brinkworth D, Qian H, Matos S, Kim HL, Abdel-Halim H, Kumar RJ, Johnston GA, Hanrahan JR. Chebib M, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):448-57. doi: 10.1124/jpet.108.146464. Epub 2008 Nov 4. J Pharmacol Exp Ther. 2009. PMID: 18984654 Free PMC article.

6

Flavonoid modulation of GABA(A) receptors.

Hanrahan JR, Chebib M, Johnston GA. Hanrahan JR, et al. Br J Pharmacol. 2011 May;163(2):234-45. doi: 10.1111/j.1476-5381.2011.01228.x. Br J Pharmacol. 2011. PMID: 21244373 Free PMC article. Review.

7

Medicinal chemistry of ρ GABAC receptors.

Ng CK, Kim HL, Gavande N, Yamamoto I, Kumar RJ, Mewett KN, Johnston GA, Hanrahan JR, Chebib M. Ng CK, et al. Future Med Chem. 2011 Feb;3(2):197-209. doi: 10.4155/fmc.10.286. Future Med Chem. 2011. PMID: 21428815 Review.

8

Modulation of ionotropic GABA receptors by 6-methoxyflavanone and 6-methoxyflavone.

Hall BJ, Karim N, Chebib M, Johnston GA, Hanrahan JR. Hall BJ, et al. Neurochem Res. 2014 Jun;39(6):1068-78. doi: 10.1007/s11064-013-1157-2. Epub 2013 Sep 29. Neurochem Res. 2014. PMID: 24078264

9

Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists: Design, Synthesis, and Pharmacology.

Gavande N, Yamamoto I, Salam NK, Ai TH, Burden PM, Johnston GA, Hanrahan JR, Chebib M. Gavande N, et al. ACS Med Chem Lett. 2010 Oct 19;2(1):11-6. doi: 10.1021/ml1001344. eCollection 2011 Jan 13. ACS Med Chem Lett. 2010. PMID: 24900248 Free PMC article.

10

Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ1 GABAC Receptors.

Gavande N, Kim HL, Doddareddy MR, Johnston GA, Chebib M, Hanrahan JR. Gavande N, et al. ACS Med Chem Lett. 2013 Feb 18;4(4):402-7. doi: 10.1021/ml300476v. eCollection 2013 Apr 11. ACS Med Chem Lett. 2013. PMID: 24900684 Free PMC article.

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