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Page 1
Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production.
Hu LY, Lei HJ, Du D, Johnson TR, Fedij V, Kostlan C, Yue WS, Lovdahl M, Li JJ, Carroll M, Dettling D, Asbill J, Fan C, Wade K, Pocalyko D, Lapham K, Yalamanchili R, Samas B, Vrieze D, Ciotti S, Krieger-Burke T, Sliskovic D, Welgus H. Hu LY, et al. Among authors: johnson tr. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5693-7. doi: 10.1016/j.bmcl.2007.07.059. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17766112
(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.
Hu LY, Du D, Hoffman J, Smith Y, Fedij V, Kostlan C, Johnson TR, Huang Y, Kesten S, Harter W, Yue WS, Li JJ, Barvian N, Mitchell L, Lei HJ, Lefker B, Carroll M, Dettling D, Krieger-Burke T, Samas B, Yalamanchili R, Lapham K, Pocalyko D, Sliskovic D, Ciotti S, Stoller B, Hena MA, Ding Q, Maiti SN, Stier M, Welgus H. Hu LY, et al. Among authors: johnson tr. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5983-8. doi: 10.1016/j.bmcl.2007.07.075. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17827000
Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.
Li JJ, Iula DM, Nguyen MN, Hu LY, Dettling D, Johnson TR, Du DY, Shanmugasundaram V, Van Camp JA, Wang Z, Harter WG, Yue WS, Boys ML, Wade KJ, Drummond EM, Samas BM, Lefker BA, Hoge GS, Lovdahl MJ, Asbill J, Carroll M, Meade MA, Ciotti SM, Krieger-Burke T. Li JJ, et al. Among authors: johnson tr. J Med Chem. 2008 Nov 13;51(21):7010-4. doi: 10.1021/jm8009316. Epub 2008 Oct 16. J Med Chem. 2008. PMID: 18921992
Rational design of a topical androgen receptor antagonist for the suppression of sebum production with properties suitable for follicular delivery.
Mitchell LH, Johnson TR, Lu GW, Du D, Datta K, Grzemski F, Shanmugasundaram V, Spence J, Wade K, Wang Z, Sun K, Lin K, Hu LY, Sexton K, Raheja N, Kostlan C, Pocalyko D. Mitchell LH, et al. Among authors: johnson tr. J Med Chem. 2010 Jun 10;53(11):4422-7. doi: 10.1021/jm9018004. J Med Chem. 2010. PMID: 20462217
Design and implementation of multicenter pediatric and congenital studies with cardiovascular magnetic resonance: Big data in smaller bodies.
DiLorenzo MP, Lee S, Rathod RH, Raimondi F, Farooqi KM, Jain SS, Samyn MM, Johnson TR, Olivieri LJ, Fogel MA, Lai WW, Renella P, Powell AJ, Buddhe S, Stafford C, Johnson JN, Helbing WA, Pushparajah K, Voges I, Muthurangu V, Miles KG, Greil G, McMahon CJ, Slesnick TC, Fonseca BM, Morris SA, Soslow JH, Grosse-Wortmann L, Beroukhim RS, Grotenhuis HB. DiLorenzo MP, et al. Among authors: johnson tr. J Cardiovasc Magn Reson. 2024 Mar 23;26(1):101041. doi: 10.1016/j.jocmr.2024.101041. Online ahead of print. J Cardiovasc Magn Reson. 2024. PMID: 38527706 Free PMC article. Review.
Limited Relationship Between Echocardiographic Measures and Electrocardiographic Markers of Left Ventricular Size in Healthy Children.
Alexander ME, Gongwer R, Trachtenberg FL, Minich LL, Triedman JK, Kaltman JR, Czosek RJ, Tristani-Firouzi M, LaPage MJ, Tsao SS, Radbill AE, DiLorenzo MP, Kovach JR, Stephenson EA, Janson C, Mao C, Salerno JC, Clark BC, Mahgerefteh J, Pilcher T, Johnson TR, Kim JJ, Valdes SO, Cain N, Jackson L, Saarel EV; Pediatric Heart Network Investigators. Alexander ME, et al. Among authors: johnson tr. Pediatr Cardiol. 2024 Jun;45(5):1055-1063. doi: 10.1007/s00246-024-03448-2. Epub 2024 Mar 23. Pediatr Cardiol. 2024. PMID: 38520508
Editorial: Women facing crises.
Endler M, Ramirez-Negrin A, Johnson TRB. Endler M, et al. Among authors: johnson trb. Int J Gynaecol Obstet. 2023 Nov;163(2):343-344. doi: 10.1002/ijgo.15163. Int J Gynaecol Obstet. 2023. PMID: 37859624 No abstract available.
588 results