Johnson RM - Search Results

1

Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella.

Johnson RM, Fais C, Parmar M, Cheruvara H, Marshall RL, Hesketh SJ, Feasey MC, Ruggerone P, Vargiu AV, Postis VLG, Muench SP, Bavro VN. Johnson RM, et al. Microorganisms. 2020 Jun 23;8(6):943. doi: 10.3390/microorganisms8060943. Microorganisms. 2020. PMID: 32585951 Free PMC article.

2

The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design.

Rawson S, McPhillie MJ, Johnson RM, Fishwick CWG, Muench SP. Rawson S, et al. Among authors: johnson rm. Acta Crystallogr D Struct Biol. 2017 Jun 1;73(Pt 6):534-540. doi: 10.1107/S2059798317004077. Epub 2017 Apr 20. Acta Crystallogr D Struct Biol. 2017. PMID: 28580915 Free PMC article.

3

The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery.

Johnson RM, Rawson S, McPhillie MJ, Fishwick CWG, Muench SP. Johnson RM, et al. Curr Med Chem. 2018;25(39):5279-5290. doi: 10.2174/0929867324666171109120526. Curr Med Chem. 2018. PMID: 29119913 Free article. Review.

4

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc₁ complexes for structure-based drug discovery.

Amporndanai K, Johnson RM, O'Neill PM, Fishwick CWG, Jamson AH, Rawson S, Muench SP, Hasnain SS, Antonyuk SV. Amporndanai K, et al. Among authors: johnson rm. IUCrJ. 2018 Feb 20;5(Pt 2):200-210. doi: 10.1107/S2052252518001616. eCollection 2018 Mar 1. IUCrJ. 2018. PMID: 29765610 Free PMC article.

5

Approaches to altering particle distributions in cryo-electron microscopy sample preparation.

Drulyte I, Johnson RM, Hesketh EL, Hurdiss DL, Scarff CA, Porav SA, Ranson NA, Muench SP, Thompson RF. Drulyte I, et al. Among authors: johnson rm. Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):560-571. doi: 10.1107/S2059798318006496. Epub 2018 May 18. Acta Crystallogr D Struct Biol. 2018. PMID: 29872006 Free PMC article. Review.

6

LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM.

Chiduza GN, Johnson RM, Wright GSA, Antonyuk SV, Muench SP, Hasnain SS. Chiduza GN, et al. Among authors: johnson rm. Acta Crystallogr D Struct Biol. 2019 Jul 1;75(Pt 7):660-669. doi: 10.1107/S2059798319009094. Epub 2019 Jun 28. Acta Crystallogr D Struct Biol. 2019. PMID: 31282475 Free PMC article.

7

Emerging Role of Electron Microscopy in Drug Discovery.

Johnson RM, Higgins AJ, Muench SP. Johnson RM, et al. Trends Biochem Sci. 2019 Oct;44(10):897-898. doi: 10.1016/j.tibs.2019.07.003. Epub 2019 Aug 10. Trends Biochem Sci. 2019. PMID: 31409563 Free article. Review. No abstract available.

8

Dimeric structures of quinol-dependent nitric oxide reductases (qNORs) revealed by cryo-electron microscopy.

Gopalasingam CC, Johnson RM, Chiduza GN, Tosha T, Yamamoto M, Shiro Y, Antonyuk SV, Muench SP, Hasnain SS. Gopalasingam CC, et al. Among authors: johnson rm. Sci Adv. 2019 Aug 28;5(8):eaax1803. doi: 10.1126/sciadv.aax1803. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31489376 Free PMC article.

9

Structure-Based Identification and Characterization of Inhibitors of the Epilepsy-Associated K_Na1.1 (KCNT1) Potassium Channel.

Cole BA, Johnson RM, Dejakaisaya H, Pilati N, Fishwick CWG, Muench SP, Lippiat JD. Cole BA, et al. Among authors: johnson rm. iScience. 2020 May 22;23(5):101100. doi: 10.1016/j.isci.2020.101100. Epub 2020 Apr 25. iScience. 2020. PMID: 32408169 Free PMC article.

10

The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer.

Jamali MAM, Gopalasingam CC, Johnson RM, Tosha T, Muramoto K, Muench SP, Antonyuk SV, Shiro Y, Hasnain SS. Jamali MAM, et al. Among authors: johnson rm. IUCrJ. 2020 Mar 21;7(Pt 3):404-415. doi: 10.1107/S2052252520003656. eCollection 2020 May 1. IUCrJ. 2020. PMID: 32431824 Free PMC article.

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