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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.
Kari V, Raul SK, Henck JM, Kitz J, Kramer F, Kosinsky RL, Übelmesser N, Mansour WY, Eggert J, Spitzner M, Najafova Z, Bastians H, Grade M, Gaedcke J, Wegwitz F, Johnsen SA. Kari V, et al. Among authors: johnsen sa. Clin Epigenetics. 2019 Jan 7;11(1):4. doi: 10.1186/s13148-018-0601-1. Clin Epigenetics. 2019. PMID: 30616689 Free PMC article.
Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription.
Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, Taipaleenmäki H, Ben-Batalla I, Scheller M, Loges S, Knapp S, Hesse E, Chiang CM, Grundhoff A, Johnsen SA. Nagarajan S, et al. Among authors: johnsen sa. Cell Rep. 2014 Jul 24;8(2):460-9. doi: 10.1016/j.celrep.2014.06.016. Epub 2014 Jul 10. Cell Rep. 2014. PMID: 25017071 Free PMC article.
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation.
Schmidt JM, Panzilius E, Bartsch HS, Irmler M, Beckers J, Kari V, Linnemann JR, Dragoi D, Hirschi B, Kloos UJ, Sass S, Theis F, Kahlert S, Johnsen SA, Sotlar K, Scheel CH. Schmidt JM, et al. Among authors: johnsen sa. Cell Rep. 2015 Jan 13;10(2):131-9. doi: 10.1016/j.celrep.2014.12.032. Epub 2015 Jan 8. Cell Rep. 2015. PMID: 25578726 Free article.
139 results