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Page 1
Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity.
de Jong SE, van Unen V, Manurung MD, Stam KA, Goeman JJ, Jochems SP, Höllt T, Pezzotti N, Mouwenda YD, Betouke Ongwe ME, Lorenz FR, Kruize YCM, Azimi S, König MH, Vilanova A, Eisemann E, Lelieveldt BPF, Roestenberg M, Sim BKL, Reinders MJT, Fendel R, Hoffman SL, Kremsner PG, Koning F, Mordmüller B, Lell B, Yazdanbakhsh M. de Jong SE, et al. Among authors: jochems sp. Nat Immunol. 2021 May;22(5):654-665. doi: 10.1038/s41590-021-00911-7. Epub 2021 Apr 22. Nat Immunol. 2021. PMID: 33888898 Clinical Trial.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM. Jochems SP, et al. J Clin Invest. 2019 Jul 30;129(10):4523-4538. doi: 10.1172/JCI128865. J Clin Invest. 2019. PMID: 31361601 Free PMC article. Clinical Trial.
Helminth infections drive heterogeneity in human type 2 and regulatory cells.
de Ruiter K, Jochems SP, Tahapary DL, Stam KA, König M, van Unen V, Laban S, Höllt T, Mbow M, Lelieveldt BPF, Koning F, Sartono E, Smit JWA, Supali T, Yazdanbakhsh M. de Ruiter K, et al. Among authors: jochems sp. Sci Transl Med. 2020 Jan 1;12(524):eaaw3703. doi: 10.1126/scitranslmed.aaw3703. Sci Transl Med. 2020. PMID: 31894102 Clinical Trial.
A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics.
Langenberg MCC, Hoogerwerf MA, Koopman JPR, Janse JJ, Kos-van Oosterhoud J, Feijt C, Jochems SP, de Dood CJ, van Schuijlenburg R, Ozir-Fazalalikhan A, Manurung MD, Sartono E, van der Beek MT, Winkel BMF, Verbeek-Menken PH, Stam KA, van Leeuwen FWB, Meij P, van Diepen A, van Lieshout L, van Dam GJ, Corstjens PLAM, Hokke CH, Yazdanbakhsh M, Visser LG, Roestenberg M. Langenberg MCC, et al. Among authors: jochems sp. Nat Med. 2020 Mar;26(3):326-332. doi: 10.1038/s41591-020-0759-x. Epub 2020 Feb 17. Nat Med. 2020. PMID: 32066978 Clinical Trial.
COVID-19 in Africa: Dampening the storm?
Mbow M, Lell B, Jochems SP, Cisse B, Mboup S, Dewals BG, Jaye A, Dieye A, Yazdanbakhsh M. Mbow M, et al. Among authors: jochems sp. Science. 2020 Aug 7;369(6504):624-626. doi: 10.1126/science.abd3902. Science. 2020. PMID: 32764055 No abstract available.
Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon.
Mouwenda YD, Betouke Ongwe ME, Sonnet F, Stam KA, Labuda LA, De Vries S, Grobusch MP, Zinsou FJ, Honkpehedji YJ, Dejon Agobe JC, Diemert DJ, van Leeuwen R, Bottazzi ME, Hotez PJ, Kremsner PG, Bethony JM, Jochems SP, Adegnika AA, Massinga Loembe M, Yazdanbakhsh M. Mouwenda YD, et al. Among authors: jochems sp. PLoS Negl Trop Dis. 2021 Oct 1;15(10):e0009732. doi: 10.1371/journal.pntd.0009732. eCollection 2021 Oct. PLoS Negl Trop Dis. 2021. PMID: 34597297 Free PMC article. Clinical Trial.
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19.
Roukens AHE, Pothast CR, König M, Huisman W, Dalebout T, Tak T, Azimi S, Kruize Y, Hagedoorn RS, Zlei M, Staal FJT, de Bie FJ, van Dongen JJM, Arbous SM, Zhang JLH, Verheij M, Prins C, van der Does AM, Hiemstra PS, de Vries JJC, Janse JJ, Roestenberg M, Myeni SK, Kikkert M, Yazdanbakhsh M, Heemskerk MHM, Smits HH, Jochems SP; in collaboration with BEAT-COVID group; in collaboration with COVID-19 LUMC group. Roukens AHE, et al. Among authors: jochems sp. Nat Immunol. 2022 Jan;23(1):23-32. doi: 10.1038/s41590-021-01095-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937933
Inflammatory and tolerogenic myeloid cells determine outcome following human allergen challenge.
Voskamp AL, Tak T, Gerdes ML, Menafra R, Duijster E, Jochems SP, Kielbasa SM, Kormelink TG, Stam KA, van Hengel ORJ, de Jong NW, Hendriks RW, Kloet SL, Yazdanbakhsh M, de Jong EC, Gerth van Wijk R, Smits HH. Voskamp AL, et al. Among authors: jochems sp. J Exp Med. 2023 Sep 4;220(9):e20221111. doi: 10.1084/jem.20221111. Epub 2023 Jul 10. J Exp Med. 2023. PMID: 37428185 Free PMC article.
51 results