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Novel hybrid selenosulfonamides as potent antileishmanial agents.
Baquedano Y, Moreno E, Espuelas S, Nguewa P, Font M, Gutierrez KJ, Jiménez-Ruiz A, Palop JA, Sanmartín C. Baquedano Y, et al. Eur J Med Chem. 2014 Mar 3;74:116-23. doi: 10.1016/j.ejmech.2013.12.030. Epub 2014 Jan 3. Eur J Med Chem. 2014. PMID: 24448421
Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.
Rico E, Oliva C, Gutierrez KJ, Alzate JF, Genes CM, Moreno D, Casanova E, Gigante A, Pérez-Pérez MJ, Camarasa MJ, Clos J, Gago F, Jiménez-Ruiz A. Rico E, et al. PLoS One. 2014 Feb 26;9(2):e89526. doi: 10.1371/journal.pone.0089526. eCollection 2014. PLoS One. 2014. PMID: 24651293 Free PMC article.
Novel Heteroaryl Selenocyanates and Diselenides as Potent Antileishmanial Agents.
Baquedano Y, Alcolea V, Toro MÁ, Gutiérrez KJ, Nguewa P, Font M, Moreno E, Espuelas S, Jiménez-Ruiz A, Palop JA, Plano D, Sanmartín C. Baquedano Y, et al. Antimicrob Agents Chemother. 2016 May 23;60(6):3802-12. doi: 10.1128/AAC.02529-15. Print 2016 Jun. Antimicrob Agents Chemother. 2016. PMID: 27067328 Free PMC article.
First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity.
Ruiz-Santaquiteria M, Sánchez-Murcia PA, Toro MA, de Lucio H, Gutiérrez KJ, de Castro S, Carneiro FAC, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Ruiz-Santaquiteria M, et al. Eur J Med Chem. 2017 Jul 28;135:49-59. doi: 10.1016/j.ejmech.2017.04.020. Epub 2017 Apr 13. Eur J Med Chem. 2017. PMID: 28431354 Free article.
132 results