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Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities.
Garofano L, Migliozzi S, Oh YT, D'Angelo F, Najac RD, Ko A, Frangaj B, Caruso FP, Yu K, Yuan J, Zhao W, Di Stefano AL, Bielle F, Jiang T, Sims P, Suvà ML, Tang F, Su XD, Ceccarelli M, Sanson M, Lasorella A, Iavarone A. Garofano L, et al. Among authors: jiang t. Nat Cancer. 2021 Feb;2(2):141-156. doi: 10.1038/s43018-020-00159-4. Epub 2021 Jan 11. Nat Cancer. 2021. PMID: 33681822 Free PMC article.
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells.
Maciaczyk D, Picard D, Zhao L, Koch K, Herrera-Rios D, Li G, Marquardt V, Pauck D, Hoerbelt T, Zhang W, Ouwens DM, Remke M, Jiang T, Steiger HJ, Maciaczyk J, Kahlert UD. Maciaczyk D, et al. Among authors: jiang t. Br J Cancer. 2017 Jun 27;117(1):102-112. doi: 10.1038/bjc.2017.157. Epub 2017 Jun 1. Br J Cancer. 2017. PMID: 28571041 Free PMC article.
9,212 results