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Therapeutic targeting of hyaluronan in the tumor stroma.
Kultti A, Li X, Jiang P, Thompson CB, Frost GI, Shepard HM. Kultti A, et al. Among authors: jiang p. Cancers (Basel). 2012 Sep 6;4(3):873-903. doi: 10.3390/cancers4030873. Cancers (Basel). 2012. PMID: 24213471 Free PMC article.
Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.
Kultti A, Zhao C, Singha NC, Zimmerman S, Osgood RJ, Symons R, Jiang P, Li X, Thompson CB, Infante JR, Jacobetz MA, Tuveson DA, Frost GI, Shepard HM, Huang Z. Kultti A, et al. Among authors: jiang p. Biomed Res Int. 2014;2014:817613. doi: 10.1155/2014/817613. Epub 2014 Jul 24. Biomed Res Int. 2014. PMID: 25147816 Free PMC article.
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA. Jacobetz MA, et al. Among authors: jiang p. Gut. 2013 Jan;62(1):112-20. doi: 10.1136/gutjnl-2012-302529. Epub 2012 Mar 30. Gut. 2013. PMID: 22466618 Free PMC article.
Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.
Hingorani SR, Harris WP, Beck JT, Berdov BA, Wagner SA, Pshevlotsky EM, Tjulandin SA, Gladkov OA, Holcombe RF, Korn R, Raghunand N, Dychter S, Jiang P, Shepard HM, Devoe CE. Hingorani SR, et al. Among authors: jiang p. Clin Cancer Res. 2016 Jun 15;22(12):2848-54. doi: 10.1158/1078-0432.CCR-15-2010. Epub 2016 Jan 26. Clin Cancer Res. 2016. PMID: 26813359 Free PMC article. Clinical Trial.
Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer.
Whatcott CJ, Diep CH, Jiang P, Watanabe A, LoBello J, Sima C, Hostetter G, Shepard HM, Von Hoff DD, Han H. Whatcott CJ, et al. Among authors: jiang p. Clin Cancer Res. 2015 Aug 1;21(15):3561-8. doi: 10.1158/1078-0432.CCR-14-1051. Epub 2015 Feb 18. Clin Cancer Res. 2015. PMID: 25695692 Free PMC article.
5,157 results