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Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.
Yuan X, Jiang H, Fu D, Rech JC, Robida A, Rajanayake K, Yuan H, He M, Wen B, Sun D, Liu C, Chinnaswamy K, Stuckey JA, Paczesny S, Yang CY. Yuan X, et al. Among authors: jiang h. ACS Pharmacol Transl Sci. 2023 Aug 16;6(9):1275-1287. doi: 10.1021/acsptsci.3c00122. eCollection 2023 Sep 8. ACS Pharmacol Transl Sci. 2023. PMID: 37705593
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.
Yuan X, Jiang H, Fu D, Robida A, Rajanayake K, Yuan H, Wen B, Sun D, Watch BT, Chinnaswamy K, Stuckey JA, Paczesny S, Rech JC, Yang CY. Yuan X, et al. Among authors: jiang h. Bioorg Med Chem. 2022 Oct 1;71:116942. doi: 10.1016/j.bmc.2022.116942. Epub 2022 Jul 22. Bioorg Med Chem. 2022. PMID: 35930851 Free PMC article.
Granzyme A-producing T helper cells are critical for acute graft-versus-host disease.
Park S, Griesenauer B, Jiang H, Adom D, Mehrpouya-Bahrami P, Chakravorty S, Kazemian M, Imam T, Srivastava R, Hayes TA, Pardo J, Janga SC, Paczesny S, Kaplan MH, Olson MR. Park S, et al. Among authors: jiang h. JCI Insight. 2020 Sep 17;5(18):e124465. doi: 10.1172/jci.insight.124465. JCI Insight. 2020. PMID: 32809971 Free PMC article.
ST2 as checkpoint target for colorectal cancer immunotherapy.
Van der Jeught K, Sun Y, Fang Y, Zhou Z, Jiang H, Yu T, Yang J, Kamocka MM, So KM, Li Y, Eyvani H, Sandusky GE, Frieden M, Braun H, Beyaert R, He X, Zhang X, Zhang C, Paczesny S, Lu X. Van der Jeught K, et al. Among authors: jiang h. JCI Insight. 2020 May 7;5(9):e136073. doi: 10.1172/jci.insight.136073. JCI Insight. 2020. PMID: 32376804 Free PMC article.
27,224 results
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