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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 2
2011 2
2012 1
2013 4
2014 2
2015 3
2016 2
2017 5
2018 1
2019 1
2020 3
2021 2
2022 4
2023 2
2024 1

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31 results

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Page 1
Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents.
Prieto-Díaz R, Fojo-Carballo H, Majellaro M, Tandarić T, Azuaje J, Brea J, Loza MI, Barbazán J, Salort G, Chotalia M, Rodríguez-Pampín I, Mallo-Abreu A, Rita Paleo M, García-Mera X, Ciruela F, Gutiérrez-de-Terán H, Sotelo E. Prieto-Díaz R, et al. Among authors: azuaje j. Biomed Pharmacother. 2024 Apr;173:116345. doi: 10.1016/j.biopha.2024.116345. Epub 2024 Mar 5. Biomed Pharmacother. 2024. PMID: 38442670 Free article.
Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs.
Gioé-Gallo C, Ortigueira S, Brea J, Raïch I, Azuaje J, Paleo MR, Majellaro M, Loza MI, Salas CO, García-Mera X, Navarro G, Sotelo E. Gioé-Gallo C, et al. Among authors: azuaje j. Biomed Pharmacother. 2023 Aug;164:114934. doi: 10.1016/j.biopha.2023.114934. Epub 2023 May 24. Biomed Pharmacother. 2023. PMID: 37236027 Free article.
Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists.
Prieto-Díaz R, González-Gómez M, Fojo-Carballo H, Azuaje J, El Maatougui A, Majellaro M, Loza MI, Brea J, Fernández-Dueñas V, Paleo MR, Díaz-Holguín A, Garcia-Pinel B, Mallo-Abreu A, Estévez JC, Andújar-Arias A, García-Mera X, Gomez-Tourino I, Ciruela F, Salas CO, Gutiérrez-de-Terán H, Sotelo E. Prieto-Díaz R, et al. Among authors: azuaje j. J Med Chem. 2023 Jan 12;66(1):890-912. doi: 10.1021/acs.jmedchem.2c01768. Epub 2022 Dec 14. J Med Chem. 2023. PMID: 36517209 Free PMC article.
A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models.
Tay AHM, Prieto-Díaz R, Neo S, Tong L, Chen X, Carannante V, Önfelt B, Hartman J, Haglund F, Majellaro M, Azuaje J, Garcia-Mera X, Brea JM, Loza MI, Jespers W, Gutierrez-de-Teran H, Sotelo E, Lundqvist A. Tay AHM, et al. Among authors: azuaje j. J Immunother Cancer. 2022 May;10(5):e004592. doi: 10.1136/jitc-2022-004592. J Immunother Cancer. 2022. PMID: 35580926 Free PMC article.
Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3 Antagonists.
Miranda-Pastoriza D, Bernárdez R, Azuaje J, Prieto-Díaz R, Majellaro M, Tamhankar AV, Koenekoop L, González A, Gioé-Gallo C, Mallo-Abreu A, Brea J, Loza MI, García-Rey A, García-Mera X, Gutiérrez-de-Terán H, Sotelo E. Miranda-Pastoriza D, et al. Among authors: azuaje j. ACS Med Chem Lett. 2022 Jan 10;13(2):243-249. doi: 10.1021/acsmedchemlett.1c00598. eCollection 2022 Feb 10. ACS Med Chem Lett. 2022. PMID: 35178181 Free PMC article.
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists.
Val C, Rodríguez-García C, Prieto-Díaz R, Crespo A, Azuaje J, Carbajales C, Majellaro M, Díaz-Holguín A, Brea JM, Loza MI, Gioé-Gallo C, Contino M, Stefanachi A, García-Mera X, Estévez JC, Gutiérrez-de-Terán H, Sotelo E. Val C, et al. Among authors: azuaje j. J Med Chem. 2022 Feb 10;65(3):2091-2106. doi: 10.1021/acs.jmedchem.1c01636. Epub 2022 Jan 22. J Med Chem. 2022. PMID: 35068155 Free PMC article.
Potent and Subtype-Selective Dopamine D2 Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach.
Mallo-Abreu A, Reyes-Resina I, Azuaje J, Franco R, García-Rey A, Majellaro M, Miranda-Pastoriza D, García-Mera X, Jespers W, Gutiérrez-de-Terán H, Navarro G, Sotelo E. Mallo-Abreu A, et al. Among authors: azuaje j. J Med Chem. 2021 Jun 24;64(12):8710-8726. doi: 10.1021/acs.jmedchem.1c00704. Epub 2021 Jun 10. J Med Chem. 2021. PMID: 34110150 Free PMC article.
3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition.
Majellaro M, Jespers W, Crespo A, Núñez MJ, Novio S, Azuaje J, Prieto-Díaz R, Gioé C, Alispahic B, Brea J, Loza MI, Freire-Garabal M, Garcia-Santiago C, Rodríguez-García C, García-Mera X, Caamaño O, Fernandez-Masaguer C, Sardina JF, Stefanachi A, El Maatougui A, Mallo-Abreu A, Åqvist J, Gutiérrez-de-Terán H, Sotelo E. Majellaro M, et al. Among authors: azuaje j. J Med Chem. 2021 Jan 14;64(1):458-480. doi: 10.1021/acs.jmedchem.0c01431. Epub 2020 Dec 29. J Med Chem. 2021. PMID: 33372800
X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists.
Jespers W, Verdon G, Azuaje J, Majellaro M, Keränen H, García-Mera X, Congreve M, Deflorian F, de Graaf C, Zhukov A, Doré AS, Mason JS, Åqvist J, Cooke RM, Sotelo E, Gutiérrez-de-Terán H. Jespers W, et al. Among authors: azuaje j. Angew Chem Int Ed Engl. 2020 Sep 14;59(38):16536-16543. doi: 10.1002/anie.202003788. Epub 2020 Jul 22. Angew Chem Int Ed Engl. 2020. PMID: 32542862 Free PMC article.
31 results