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Page 1
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
Sato S, Dyar KA, Treebak JT, Jepsen SL, Ehrlich AM, Ashcroft SP, Trost K, Kunzke T, Prade VM, Small L, Basse AL, Schönke M, Chen S, Samad M, Baldi P, Barrès R, Walch A, Moritz T, Holst JJ, Lutter D, Zierath JR, Sassone-Corsi P. Sato S, et al. Among authors: jepsen sl. Cell Metab. 2022 Feb 1;34(2):329-345.e8. doi: 10.1016/j.cmet.2021.12.016. Epub 2022 Jan 13. Cell Metab. 2022. PMID: 35030324 Free article.
Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis.
Galsgaard KD, Winther-Sørensen M, Ørskov C, Kissow H, Poulsen SS, Vilstrup H, Prehn C, Adamski J, Jepsen SL, Hartmann B, Hunt J, Charron MJ, Pedersen J, Wewer Albrechtsen NJ, Holst JJ. Galsgaard KD, et al. Among authors: jepsen sl. Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E93-E103. doi: 10.1152/ajpendo.00198.2017. Epub 2017 Oct 3. Am J Physiol Endocrinol Metab. 2018. PMID: 28978545 Free PMC article.
Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.
Kuhre RE, Wewer Albrechtsen NJ, Larsen O, Jepsen SL, Balk-Møller E, Andersen DB, Deacon CF, Schoonjans K, Reimann F, Gribble FM, Albrechtsen R, Hartmann B, Rosenkilde MM, Holst JJ. Kuhre RE, et al. Among authors: jepsen sl. Mol Metab. 2018 May;11:84-95. doi: 10.1016/j.molmet.2018.03.007. Epub 2018 Mar 17. Mol Metab. 2018. PMID: 29656109 Free PMC article.
Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1.
Jepsen SL, Vestergaard ET, Larraufie P, Gribble FM, Reimann F, Jørgensen JOL, Holst JJ, Kuhre RE. Jepsen SL, et al. J Clin Endocrinol Metab. 2020 Jan 1;105(1):266-75. doi: 10.1210/clinem/dgz046. J Clin Endocrinol Metab. 2020. PMID: 31608930 Free PMC article. Clinical Trial.
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
Winther-Sørensen M, Galsgaard KD, Santos A, Trammell SAJ, Sulek K, Kuhre RE, Pedersen J, Andersen DB, Hassing AS, Dall M, Treebak JT, Gillum MP, Torekov SS, Windeløv JA, Hunt JE, Kjeldsen SAS, Jepsen SL, Vasilopoulou CG, Knop FK, Ørskov C, Werge MP, Bisgaard HC, Eriksen PL, Vilstrup H, Gluud LL, Holst JJ, Wewer Albrechtsen NJ. Winther-Sørensen M, et al. Among authors: jepsen sl. Mol Metab. 2020 Dec;42:101080. doi: 10.1016/j.molmet.2020.101080. Epub 2020 Sep 13. Mol Metab. 2020. PMID: 32937194 Free PMC article.
Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms.
Modvig IM, Kuhre RE, Jepsen SL, Xu SFS, Engelstoft MS, Egerod KL, Schwartz TW, Ørskov C, Rosenkilde MM, Holst JJ. Modvig IM, et al. Among authors: jepsen sl. Am J Physiol Endocrinol Metab. 2021 May 1;320(5):E874-E885. doi: 10.1152/ajpendo.00026.2021. Epub 2021 Mar 1. Am J Physiol Endocrinol Metab. 2021. PMID: 33645250 Free article.
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
Kuhre RE, Modvig IM, Jepsen SL, Kizilkaya HS, Bæch-Laursen C, Smith CA, Reimann F, Gribble FM, Rosenkilde MM, Holst JJ. Kuhre RE, et al. Among authors: jepsen sl. Front Endocrinol (Lausanne). 2021 Aug 5;12:690387. doi: 10.3389/fendo.2021.690387. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34421821 Free PMC article.
28 results