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Proteomics of immune cells from liver tumors reveals immunotherapy targets.
Canale FP, Neumann J, von Renesse J, Loggi E, Pecoraro M, Vogel I, Zoppi G, Antonini G, Wolf T, Jin W, Zheng X, La Barba G, Birgin E, Forkel M, Nilsson T, Marone R, Mueller H, Pelletier N, Jeker LT, Civenni G, Schlapbach C, Catapano CV, Seifert L, Seifert AM, Gillessen S, De Dosso S, Cristaudi A, Rahbari NN, Ercolani G, Geiger R. Canale FP, et al. Among authors: jeker lt. Cell Genom. 2023 May 30;3(6):100331. doi: 10.1016/j.xgen.2023.100331. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388918 Free PMC article.
Leveraging microRNAs for cellular therapy.
Hasiuk M, Dölz M, Marone R, Jeker LT. Hasiuk M, et al. Among authors: jeker lt. Immunol Lett. 2023 Oct;262:27-35. doi: 10.1016/j.imlet.2023.08.005. Epub 2023 Sep 3. Immunol Lett. 2023. PMID: 37660892 Free article.
Melanoma clonal heterogeneity leads to secondary resistance after adoptive cell therapy with tumor-infiltrating lymphocytes.
König D, Sandholzer M, Uzun S, Zingg A, Ritschard R, Thut H, Glatz K, Kappos EA, Schaefer DJ, Kettelhack C, Passweg JR, Holbro A, Baur K, Medinger M, Buser A, Lardinois D, Jeker LT, Khanna N, Stenner F, Kasenda B, Homicsko K, Matter M, Rodrigues Mantuano N, Zippelius A, Läubli H. König D, et al. Among authors: jeker lt. Cancer Immunol Res. 2024 Apr 17. doi: 10.1158/2326-6066.CIR-23-0757. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38631025
TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf.
Chang Y, Bach L, Hasiuk M, Wen L, Elmzzahi T, Tsui C, Gutiérrez-Melo N, Steffen T, Utzschneider DT, Raj T, Jost PJ, Heink S, Cheng J, Burton OT, Zeiträg J, Alterauge D, Dahlström F, Becker JC, Kastl M, Symeonidis K, van Uelft M, Becker M, Reschke S, Krebs S, Blum H, Abdullah Z, Paeschke K, Ohnmacht C, Neumann C, Liston A, Meissner F, Korn T, Hasenauer J, Heissmeyer V, Beyer M, Kallies A, Jeker LT, Baumjohann D. Chang Y, et al. Among authors: jeker lt. Sci Immunol. 2024 Mar;9(93):eadd4818. doi: 10.1126/sciimmunol.add4818. Epub 2024 Mar 1. Sci Immunol. 2024. PMID: 38427718
Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy.
Marone R, Landmann E, Devaux A, Lepore R, Seyres D, Zuin J, Burgold T, Engdahl C, Capoferri G, Dell'Aglio A, Larrue C, Simonetta F, Rositzka J, Rhiel M, Andrieux G, Gallagher DN, Schröder MS, Wiederkehr A, Sinopoli A, Do Sacramento V, Haydn A, Garcia-Prat L, Divsalar C, Camus A, Xu L, Bordoli L, Schwede T, Porteus M, Tamburini J, Corn JE, Cathomen T, Cornu TI, Urlinger S, Jeker LT. Marone R, et al. Among authors: jeker lt. J Exp Med. 2023 Dec 4;220(12):e20231235. doi: 10.1084/jem.20231235. Epub 2023 Sep 29. J Exp Med. 2023. PMID: 37773046 Free PMC article.
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Trefny MP, Kirchhammer N, Auf der Maur P, Natoli M, Schmid D, Germann M, Fernandez Rodriguez L, Herzig P, Lötscher J, Akrami M, Stinchcombe JC, Stanczak MA, Zingg A, Buchi M, Roux J, Marone R, Don L, Lardinois D, Wiese M, Jeker LT, Bentires-Alj M, Rossy J, Thommen DS, Griffiths GM, Läubli H, Hess C, Zippelius A. Trefny MP, et al. Among authors: jeker lt. Nat Commun. 2023 Feb 2;14(1):86. doi: 10.1038/s41467-022-35583-w. Nat Commun. 2023. PMID: 36732507 Free PMC article.
38 results