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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 1
2012 2
2013 2
2014 2
2015 2
2016 1
2018 1
2019 1
2021 5
2022 6
2023 1
2024 2

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22 results

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Page 1
Novel spirocyclic dimer, SpiD3, targets chronic lymphocytic leukemia survival pathways with potent preclinical effects.
Eiken AP, Smith AL, Skupa SA, Schmitz E, Rana S, Singh S, Kumar S, Mallareddy JR, de Cubas AA, Krishna A, Kalluchi A, Rowley MJ, D'Angelo CR, Lunning MA, Bociek RG, Vose JM, Natarajan A, El-Gamal D. Eiken AP, et al. Among authors: mallareddy jr. Cancer Res Commun. 2024 Apr 30. doi: 10.1158/2767-9764.CRC-24-0071. Online ahead of print. Cancer Res Commun. 2024. PMID: 38687198 Free article.
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.
Mullen NJ, Shukla SK, Thakur R, Kollala SS, Wang D, Chaika N, Santana JF, Miklavcic WR, LaBreck DA, Mallareddy JR, Price DH, Natarajan A, Mehla K, Sykes DB, Hollingsworth MA, Singh PK. Mullen NJ, et al. Among authors: mallareddy jr. bioRxiv [Preprint]. 2024 Jan 13:2023.04.03.535399. doi: 10.1101/2023.04.03.535399. bioRxiv. 2024. PMID: 37066260 Free PMC article. Preprint.
Systemic Administration of a Brain Permeable Cdk5 Inhibitor Alters Neurobehavior.
Umfress A, Singh S, Ryan KJ, Chakraborti A, Plattner F, Sonawane Y, Mallareddy JR, Acosta EP, Natarajan A, Bibb JA. Umfress A, et al. Among authors: mallareddy jr. Front Pharmacol. 2022 May 12;13:863762. doi: 10.3389/fphar.2022.863762. eCollection 2022. Front Pharmacol. 2022. PMID: 35645825 Free PMC article.
Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
Napoleon JV, Sagar S, Kubica SP, Boghean L, Kour S, King HM, Sonawane YA, Crawford AJ, Gautam N, Kizhake S, Bialk PA, Kmiec E, Mallareddy JR, Patil PP, Rana S, Singh S, Prahlad J, Grandgenett PM, Borgstahl GEO, Ghosal G, Alnouti Y, Hollingsworth MA, Radhakrishnan P, Natarajan A. Napoleon JV, et al. Among authors: mallareddy jr. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115071119. doi: 10.1073/pnas.2115071119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476515 Free PMC article.
Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells.
Kour S, Rana S, Kubica SP, Kizhake S, Ahmad M, Muñoz-Trujillo C, Klinkebiel D, Singh S, Mallareddy JR, Chandra S, Woods NT, Karpf AR, Natarajan A. Kour S, et al. Among authors: mallareddy jr. J Biol Chem. 2022 May;298(5):101890. doi: 10.1016/j.jbc.2022.101890. Epub 2022 Apr 1. J Biol Chem. 2022. PMID: 35378132 Free PMC article.
22 results