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G protein-coupled receptor modulation with pepducins: moving closer to the clinic.
Dimond P, Carlson K, Bouvier M, Gerard C, Xu L, Covic L, Agarwal A, Ernst OP, Janz JM, Schwartz TW, Gardella TJ, Milligan G, Kuliopulos A, Sakmar TP, Hunt SW 3rd. Dimond P, et al. Among authors: janz jm. Ann N Y Acad Sci. 2011 May;1226:34-49. doi: 10.1111/j.1749-6632.2011.06039.x. Ann N Y Acad Sci. 2011. PMID: 21615752
Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.
Tchernychev B, Ren Y, Sachdev P, Janz JM, Haggis L, O'Shea A, McBride E, Looby R, Deng Q, McMurry T, Kazmi MA, Sakmar TP, Hunt S 3rd, Carlson KE. Tchernychev B, et al. Among authors: janz jm. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22255-9. doi: 10.1073/pnas.1009633108. Epub 2010 Dec 7. Proc Natl Acad Sci U S A. 2010. PMID: 21139054 Free PMC article.
19 results