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The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes.
Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ, Jeltsch A, Shinkai Y, Falnes PØ. Davydova E, et al. Among authors: jakobsson me. Nat Commun. 2021 Feb 9;12(1):891. doi: 10.1038/s41467-020-20670-7. Nat Commun. 2021. PMID: 33563959 Free PMC article.
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).
Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sørensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PØ. Malecki J, et al. Among authors: jakobsson me. Nucleic Acids Res. 2017 May 5;45(8):4370-4389. doi: 10.1093/nar/gkx002. Nucleic Acids Res. 2017. PMID: 28108655 Free PMC article.
28 results