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Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.
Berulava T, Buchholz E, Elerdashvili V, Pena T, Islam MR, Lbik D, Mohamed BA, Renner A, von Lewinski D, Sacherer M, Bohnsack KE, Bohnsack MT, Jain G, Capece V, Cleve N, Burkhardt S, Hasenfuss G, Fischer A, Toischer K. Berulava T, et al. Among authors: jain g. Eur J Heart Fail. 2020 Jan;22(1):54-66. doi: 10.1002/ejhf.1672. Epub 2019 Dec 17. Eur J Heart Fail. 2020. PMID: 31849158 Free article.
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.
Benito E, Urbanke H, Ramachandran B, Barth J, Halder R, Awasthi A, Jain G, Capece V, Burkhardt S, Navarro-Sala M, Nagarajan S, Schütz AL, Johnsen SA, Bonn S, Lührmann R, Dean C, Fischer A. Benito E, et al. Among authors: jain g. J Clin Invest. 2015 Sep;125(9):3572-84. doi: 10.1172/JCI79942. Epub 2015 Aug 17. J Clin Invest. 2015. PMID: 26280576 Free PMC article.
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.
Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: jain g. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.
Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.
Agís-Balboa RC, Pinheiro PS, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, Pape JC, Binder EB, Mulle C, Fischer A, Sananbenesi F. Agís-Balboa RC, et al. Among authors: jain g. EMBO J. 2017 Oct 2;36(19):2815-2828. doi: 10.15252/embj.201796821. Epub 2017 Aug 2. EMBO J. 2017. PMID: 28768717 Free PMC article.
Innate immune memory in the brain shapes neurological disease hallmarks.
Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ. Wendeln AC, et al. Among authors: jain g. Nature. 2018 Apr;556(7701):332-338. doi: 10.1038/s41586-018-0023-4. Epub 2018 Apr 11. Nature. 2018. PMID: 29643512 Free PMC article.
miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons.
Roser AE, Caldi Gomes L, Halder R, Jain G, Maass F, Tönges L, Tatenhorst L, Bähr M, Fischer A, Lingor P. Roser AE, et al. Among authors: jain g. Mol Ther Nucleic Acids. 2018 Jun 1;11:9-22. doi: 10.1016/j.omtn.2018.01.005. Epub 2018 Feb 2. Mol Ther Nucleic Acids. 2018. PMID: 29858093 Free PMC article.
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Paiva I, Jain G, Lázaro DF, Jerčić KG, Hentrich T, Kerimoglu C, Pinho R, Szegő ÈM, Burkhardt S, Capece V, Halder R, Islam R, Xylaki M, Caldi Gomes LA, Roser AE, Lingor P, Schulze-Hentrich JM, Borovečki F, Fischer A, Outeiro TF. Paiva I, et al. Among authors: jain g. Neurobiol Dis. 2018 Nov;119:121-135. doi: 10.1016/j.nbd.2018.08.001. Epub 2018 Aug 6. Neurobiol Dis. 2018. PMID: 30092270
Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia.
Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J. Chowdhury A, et al. Among authors: jain g. Cell Rep. 2018 Oct 16;25(3):561-570.e6. doi: 10.1016/j.celrep.2018.09.057. Cell Rep. 2018. PMID: 30332638 Free PMC article.
551 results