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mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. Cho S, et al. Among authors: jaffrey sr. Mol Cell. 2021 May 20;81(10):2064-2075.e8. doi: 10.1016/j.molcel.2021.03.010. Epub 2021 Mar 22. Mol Cell. 2021. PMID: 33756105 Free PMC article.
5' UTR m(6)A Promotes Cap-Independent Translation.
Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian SB, Jaffrey SR. Meyer KD, et al. Among authors: jaffrey sr. Cell. 2015 Nov 5;163(4):999-1010. doi: 10.1016/j.cell.2015.10.012. Epub 2015 Oct 22. Cell. 2015. PMID: 26593424 Free PMC article.
Reversible methylation of m6Am in the 5' cap controls mRNA stability.
Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur JJ, Chen Q, Gross SS, Elemento O, Debart F, Kiledjian M, Jaffrey SR. Mauer J, et al. Among authors: jaffrey sr. Nature. 2017 Jan 19;541(7637):371-375. doi: 10.1038/nature21022. Epub 2016 Dec 21. Nature. 2017. PMID: 28002401 Free PMC article.
Rethinking m6A Readers, Writers, and Erasers.
Meyer KD, Jaffrey SR. Meyer KD, et al. Among authors: jaffrey sr. Annu Rev Cell Dev Biol. 2017 Oct 6;33:319-342. doi: 10.1146/annurev-cellbio-100616-060758. Epub 2017 Jul 31. Annu Rev Cell Dev Biol. 2017. PMID: 28759256 Free PMC article. Review.
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.
Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, Schulman J, Famulare C, Patel M, Klimek VM, Garrett-Bakelman FE, Melnick A, Carroll M, Mason CE, Jaffrey SR, Kharas MG. Vu LP, et al. Among authors: jaffrey sr. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18. Nat Med. 2017. PMID: 28920958 Free PMC article.
178 results