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Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders.
Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC Jr, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Horiuchi Y, et al. Among authors: jaffe ae. Neurosci Res. 2013 Dec;77(4):247-50. doi: 10.1016/j.neures.2013.09.010. Epub 2013 Oct 11. Neurosci Res. 2013. PMID: 24120685 Free PMC article.
Genetic risk mechanisms of posttraumatic stress disorder in the human brain.
Bharadwaj RA, Jaffe AE, Chen Q, Deep-Soboslay A, Goldman AL, Mighdoll MI, Cotoia JA, Brandtjen AC, Shin J, Hyde TM, Mattay VS, Weinberger DR, Kleinman JE. Bharadwaj RA, et al. Among authors: jaffe ae. J Neurosci Res. 2018 Jan;96(1):21-30. doi: 10.1002/jnr.23957. Epub 2016 Oct 24. J Neurosci Res. 2018. PMID: 27775175
qSVA framework for RNA quality correction in differential expression analysis.
Jaffe AE, Tao R, Norris AL, Kealhofer M, Nellore A, Shin JH, Kim D, Jia Y, Hyde TM, Kleinman JE, Straub RE, Leek JT, Weinberger DR. Jaffe AE, et al. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7130-7135. doi: 10.1073/pnas.1617384114. Epub 2017 Jun 20. Proc Natl Acad Sci U S A. 2017. PMID: 28634288 Free PMC article.
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.
Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; BrainSeq Consortium; Cross AJ, Brandon NJ, Leek JT, Hyde TM, Kleinman JE, Weinberger DR. Jaffe AE, et al. Nat Neurosci. 2018 Aug;21(8):1117-1125. doi: 10.1038/s41593-018-0197-y. Epub 2018 Jul 26. Nat Neurosci. 2018. PMID: 30050107 Free PMC article.
Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition.
Zink CF, Barker PB, Sawa A, Weinberger DR, Wang M, Quillian H, Ulrich WS, Chen Q, Jaffe AE, Kleinman JE, Hyde TM, Prettyman GE, Giegerich M, Carta K, van Ginkel M, Bigos KL. Zink CF, et al. Among authors: jaffe ae. Am J Psychiatry. 2020 Dec 1;177(12):1129-1139. doi: 10.1176/appi.ajp.2020.19111152. Am J Psychiatry. 2020. PMID: 33256444
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing.
Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC; Brain Somatic Mosaicism Network; Park PJ, Walsh CA. Rodin RE, et al. Nat Neurosci. 2021 Feb;24(2):176-185. doi: 10.1038/s41593-020-00765-6. Epub 2021 Jan 11. Nat Neurosci. 2021. PMID: 33432195 Free PMC article.
Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia.
Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, Sloan S, Fiston-Lavier AS, Mariani J, Petrov D, Barres BA, Duncan L, Abyzov A, Vogel H; Brain Somatic Mosaicism Network; Moran JV, Vaccarino FM, Tamminga CA, Levinson DF, Urban AE. Zhu X, et al. Nat Neurosci. 2021 Feb;24(2):186-196. doi: 10.1038/s41593-020-00767-4. Epub 2021 Jan 11. Nat Neurosci. 2021. PMID: 33432196 Free PMC article.
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing.
Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC; Brain Somatic Mosaicism Network; Park PJ, Walsh CA. Rodin RE, et al. Nat Neurosci. 2021 Apr;24(4):611. doi: 10.1038/s41593-021-00830-8. Nat Neurosci. 2021. PMID: 33753946 Free PMC article. No abstract available.
221 results