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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
Srivastava S, Furlan SN, Jaeger-Ruckstuhl CA, Sarvothama M, Berger C, Smythe KS, Garrison SM, Specht JM, Lee SM, Amezquita RA, Voillet V, Muhunthan V, Yechan-Gunja S, Pillai SPS, Rader C, Houghton AM, Pierce RH, Gottardo R, Maloney DG, Riddell SR. Srivastava S, et al. Among authors: jaeger ruckstuhl ca. Cancer Cell. 2021 Feb 8;39(2):193-208.e10. doi: 10.1016/j.ccell.2020.11.005. Epub 2020 Dec 24. Cancer Cell. 2021. PMID: 33357452 Free PMC article.
Engineering and functionalization of large circular tandem repeat protein nanoparticles.
Correnti CE, Hallinan JP, Doyle LA, Ruff RO, Jaeger-Ruckstuhl CA, Xu Y, Shen BW, Qu A, Polkinghorn C, Friend DJ, Bandaranayake AD, Riddell SR, Kaiser BK, Stoddard BL, Bradley P. Correnti CE, et al. Among authors: jaeger ruckstuhl ca. Nat Struct Mol Biol. 2020 Apr;27(4):342-350. doi: 10.1038/s41594-020-0397-5. Epub 2020 Mar 23. Nat Struct Mol Biol. 2020. PMID: 32203491 Free PMC article.
TNIK signaling imprints CD8+ T cell memory formation early after priming.
Jaeger-Ruckstuhl CA, Hinterbrandner M, Höpner S, Correnti CE, Lüthi U, Friedli O, Freigang S, Al Sayed MF, Bührer ED, Amrein MA, Schürch CM, Radpour R, Riether C, Ochsenbein AF. Jaeger-Ruckstuhl CA, et al. Nat Commun. 2020 Apr 2;11(1):1632. doi: 10.1038/s41467-020-15413-7. Nat Commun. 2020. PMID: 32242021 Free PMC article.
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks.
Jaeger-Ruckstuhl CA, Lo Y, Fulton E, Waltner OG, Shabaneh TB, Simon S, Muthuraman PV, Correnti CE, Newsom OJ, Engstrom IA, Kanaan SB, Bhise SS, Peralta JMC, Ruff R, Price JP, Stull SM, Stevens AR, Bugos G, Kluesner MG, Voillet V, Muhunthan V, Morrish F, Olson JM, Gottardo R, Sarthy JF, Henikoff S, Sullivan LB, Furlan SN, Riddell SR. Jaeger-Ruckstuhl CA, et al. Immunity. 2024 Feb 13;57(2):287-302.e12. doi: 10.1016/j.immuni.2024.01.011. Immunity. 2024. PMID: 38354704 Free article.