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Fast-acting chemical tools to delineate causality in transcriptional control.
Mol Cell. 2021 Apr 15;81(8):1617-1630. doi: 10.1016/j.molcel.2021.02.015. Epub 2021 Mar 8.
Mol Cell. 2021.
PMID: 33689749
Free article.
Review.
Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders.
Ishoey M, Chorn S, Singh N, Jaeger MG, Brand M, Paulk J, Bauer S, Erb MA, Parapatics K, Müller AC, Bennett KL, Ecker GF, Bradner JE, Winter GE.
Ishoey M, et al. Among authors: jaeger mg.
ACS Chem Biol. 2018 Mar 16;13(3):553-560. doi: 10.1021/acschembio.7b00969. Epub 2018 Jan 29.
ACS Chem Biol. 2018.
PMID: 29356495
Item in Clipboard
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation.
Mayor-Ruiz C, Jaeger MG, Bauer S, Brand M, Sin C, Hanzl A, Mueller AC, Menche J, Winter GE.
Mayor-Ruiz C, et al. Among authors: jaeger mg.
Mol Cell. 2019 Aug 22;75(4):849-858.e8. doi: 10.1016/j.molcel.2019.07.013.
Mol Cell. 2019.
PMID: 31442425
Free article.
Item in Clipboard
Expanding the Degradable Proteome: Designing PROTACs by the Book.
Jaeger MG, Winter GE.
Jaeger MG, et al.
Cell Chem Biol. 2020 Jan 16;27(1):14-16. doi: 10.1016/j.chembiol.2019.12.009.
Cell Chem Biol. 2020.
PMID: 31951815
Free article.
Item in Clipboard
Selective Mediator dependence of cell-type-specifying transcription.
Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler A, Gray NS, Bradner JE, Bock C, Hnisz D, Cramer P, Winter GE.
Jaeger MG, et al.
Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1.
Nat Genet. 2020.
PMID: 32483291
Free PMC article.
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Acute BAF perturbation causes immediate changes in chromatin accessibility.
Schick S, Grosche S, Kohl KE, Drpic D, Jaeger MG, Marella NC, Imrichova H, Lin JG, Hofstätter G, Schuster M, Rendeiro AF, Koren A, Petronczki M, Bock C, Müller AC, Winter GE, Kubicek S.
Schick S, et al. Among authors: jaeger mg.
Nat Genet. 2021 Mar;53(3):269-278. doi: 10.1038/s41588-021-00777-3. Epub 2021 Feb 8.
Nat Genet. 2021.
PMID: 33558760
Free PMC article.
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Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo.
Žumer K, Maier KC, Farnung L, Jaeger MG, Rus P, Winter G, Cramer P.
Žumer K, et al. Among authors: jaeger mg.
Mol Cell. 2021 Aug 5;81(15):3096-3109.e8. doi: 10.1016/j.molcel.2021.05.028. Epub 2021 Jun 18.
Mol Cell. 2021.
PMID: 34146481
Free article.
Item in Clipboard
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF.
Lazear MR, et al. Among authors: jaeger mg.
Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20.
Mol Cell. 2023.
PMID: 37084731
Free PMC article.
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