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Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris.
Bruno M, Kersten S, Bain JM, Jaeger M, Rosati D, Kruppa MD, Lowman DW, Rice PJ, Graves B, Ma Z, Jiao YN, Chowdhary A, Renieris G, van de Veerdonk FL, Kullberg BJ, Giamarellos-Bourboulis EJ, Hoischen A, Gow NAR, Brown AJP, Meis JF, Williams DL, Netea MG. Bruno M, et al. Among authors: jaeger m. Nat Microbiol. 2020 Dec;5(12):1516-1531. doi: 10.1038/s41564-020-0780-3. Epub 2020 Aug 24. Nat Microbiol. 2020. PMID: 32839538 Free PMC article.
Genetic basis for recurrent vulvo-vaginal candidiasis.
Jaeger M, Plantinga TS, Joosten LA, Kullberg BJ, Netea MG. Jaeger M, et al. Curr Infect Dis Rep. 2013 Apr;15(2):136-42. doi: 10.1007/s11908-013-0319-3. Curr Infect Dis Rep. 2013. PMID: 23354953
The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. Jaeger M, et al. Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25579795 Free PMC article.
CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.
Swamydas M, Gao JL, Break TJ, Johnson MD, Jaeger M, Rodriguez CA, Lim JK, Green NM, Collar AL, Fischer BG, Lee CC, Perfect JR, Alexander BD, Kullberg BJ, Netea MG, Murphy PM, Lionakis MS. Swamydas M, et al. Among authors: jaeger m. Sci Transl Med. 2016 Jan 20;8(322):322ra10. doi: 10.1126/scitranslmed.aac7718. Sci Transl Med. 2016. PMID: 26791948 Free PMC article.
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.
Stappers MHT, Clark AE, Aimanianda V, Bidula S, Reid DM, Asamaphan P, Hardison SE, Dambuza IM, Valsecchi I, Kerscher B, Plato A, Wallace CA, Yuecel R, Hebecker B, da Glória Teixeira Sousa M, Cunha C, Liu Y, Feizi T, Brakhage AA, Kwon-Chung KJ, Gow NAR, Zanda M, Piras M, Zanato C, Jaeger M, Netea MG, van de Veerdonk FL, Lacerda JF, Campos A, Carvalho A, Willment JA, Latgé JP, Brown GD. Stappers MHT, et al. Among authors: jaeger m. Nature. 2018 Mar 15;555(7696):382-386. doi: 10.1038/nature25974. Epub 2018 Feb 28. Nature. 2018. PMID: 29489751 Free PMC article.
A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.
Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V. Jaeger M, et al. J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206. J Infect Dis. 2019. PMID: 31241743 Free PMC article.
Recurrent Vulvovaginal Candidiasis: An Immunological Perspective.
Rosati D, Bruno M, Jaeger M, Ten Oever J, Netea MG. Rosati D, et al. Among authors: jaeger m. Microorganisms. 2020 Jan 21;8(2):144. doi: 10.3390/microorganisms8020144. Microorganisms. 2020. PMID: 31972980 Free PMC article. Review.
808 results