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EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R. Wassef M, et al. Among authors: jacques s. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867289 Free PMC article.
Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.
Trentesaux C, Fraudeau M, Pitasi CL, Lemarchand J, Jacques S, Duche A, Letourneur F, Naser E, Bailly K, Schmitt A, Perret C, Romagnolo B. Trentesaux C, et al. Among authors: jacques s. Proc Natl Acad Sci U S A. 2020 May 19;117(20):11136-11146. doi: 10.1073/pnas.1917174117. Epub 2020 May 5. Proc Natl Acad Sci U S A. 2020. PMID: 32371487 Free PMC article.
Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers.
Beinse G, Just PA, Le Frere Belda MA, Laurent-Puig P, Jacques S, Koual M, Garinet S, Leroy K, Delanoy N, Blons H, Gervais C, Durdux C, Chapron C, Goldwasser F, Terris B, Badoual C, Taly V, Bats AS, Borghese B, Alexandre J. Beinse G, et al. Among authors: jacques s. Br J Cancer. 2022 Oct;127(6):1123-1132. doi: 10.1038/s41416-022-01900-9. Epub 2022 Jun 25. Br J Cancer. 2022. PMID: 35752712 Free PMC article.
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.
Gottenberg JE, Cagnard N, Lucchesi C, Letourneur F, Mistou S, Lazure T, Jacques S, Ba N, Ittah M, Lepajolec C, Labetoulle M, Ardizzone M, Sibilia J, Fournier C, Chiocchia G, Mariette X. Gottenberg JE, et al. Among authors: jacques s. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2770-5. doi: 10.1073/pnas.0510837103. Epub 2006 Feb 13. Proc Natl Acad Sci U S A. 2006. PMID: 16477017 Free PMC article.
Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis.
Zinovieva E, Bourgain C, Kadi A, Letourneur F, Izac B, Said-Nahal R, Lebrun N, Cagnard N, Vigier A, Jacques S, Miceli-Richard C, Garchon HJ, Heath S, Charon C, Bacq D, Boland A, Zelenika D, Chiocchia G, Breban M. Zinovieva E, et al. Among authors: jacques s. PLoS Genet. 2009 Jun;5(6):e1000528. doi: 10.1371/journal.pgen.1000528. Epub 2009 Jun 19. PLoS Genet. 2009. PMID: 19543369 Free PMC article.
588 results