Jackson MA - Search Results

1

Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage.

Bedingfield SK, Colazo JM, Yu F, Liu DD, Jackson MA, Himmel LE, Cho H, Crofford LJ, Hasty KA, Duvall CL. Bedingfield SK, et al. Among authors: jackson ma. Nat Biomed Eng. 2021 Sep;5(9):1069-1083. doi: 10.1038/s41551-021-00780-3. Epub 2021 Aug 19. Nat Biomed Eng. 2021. PMID: 34413494 Free PMC article.

2

Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.

Sarett SM, Werfel TA, Lee L, Jackson MA, Kilchrist KV, Brantley-Sieders D, Duvall CL. Sarett SM, et al. Among authors: jackson ma. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6490-E6497. doi: 10.1073/pnas.1621240114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739942 Free PMC article.

3

Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes.

Jackson MA, Bedingfield SK, Yu F, Stokan ME, Miles RE, Curvino EJ, Hoogenboezem EN, Bonami RH, Patel SS, Kendall PL, Giorgio TD, Duvall CL. Jackson MA, et al. Biomaterials. 2019 Feb;192:245-259. doi: 10.1016/j.biomaterials.2018.11.010. Epub 2018 Nov 10. Biomaterials. 2019. PMID: 30458360 Free PMC article.

4

Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.

Werfel TA, Jackson MA, Kavanaugh TE, Kirkbride KC, Miteva M, Giorgio TD, Duvall C. Werfel TA, et al. Among authors: jackson ma. J Control Release. 2017 Jun 10;255:12-26. doi: 10.1016/j.jconrel.2017.03.389. Epub 2017 Mar 31. J Control Release. 2017. PMID: 28366646 Free PMC article.

5

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.

Jackson MA, Werfel TA, Curvino EJ, Yu F, Kavanaugh TE, Sarett SM, Dockery MD, Kilchrist KV, Jackson AN, Giorgio TD, Duvall CL. Jackson MA, et al. Among authors: jackson an. ACS Nano. 2017 Jun 27;11(6):5680-5696. doi: 10.1021/acsnano.7b01110. Epub 2017 Jun 7. ACS Nano. 2017. PMID: 28548843 Free PMC article.

6

Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers.

Jackson MA, Patel SS, Yu F, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu DD, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL. Jackson MA, et al. Biomaterials. 2021 Jan;268:120528. doi: 10.1016/j.biomaterials.2020.120528. Epub 2020 Nov 23. Biomaterials. 2021. PMID: 33285438 Free PMC article.

7

Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.

Sarett SM, Werfel TA, Chandra I, Jackson MA, Kavanaugh TE, Hattaway ME, Giorgio TD, Duvall CL. Sarett SM, et al. Among authors: jackson ma. Biomaterials. 2016 Aug;97:122-32. doi: 10.1016/j.biomaterials.2016.04.017. Epub 2016 Apr 21. Biomaterials. 2016. PMID: 27163624 Free PMC article.

8

Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.

Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL. Werfel TA, et al. Among authors: jackson ma. Cancer Res. 2018 Apr 1;78(7):1845-1858. doi: 10.1158/0008-5472.CAN-17-2388. Epub 2018 Jan 22. Cancer Res. 2018. PMID: 29358172 Free PMC article.

9

Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.

Kilchrist KV, Dimobi SC, Jackson MA, Evans BC, Werfel TA, Dailing EA, Bedingfield SK, Kelly IB, Duvall CL. Kilchrist KV, et al. Among authors: jackson ma. ACS Nano. 2019 Feb 26;13(2):1136-1152. doi: 10.1021/acsnano.8b05482. Epub 2019 Jan 18. ACS Nano. 2019. PMID: 30629431 Free PMC article.

10

DNA Polyplexes of a Phosphorylcholine-Based Zwitterionic Polymer for Gene Delivery.

Dave KM, Han L, Jackson MA, Kadlecik L, Duvall CL, S Manickam D. Dave KM, et al. Among authors: jackson ma. Pharm Res. 2020 Aug 28;37(9):176. doi: 10.1007/s11095-020-02899-5. Pharm Res. 2020. PMID: 32860072 Free PMC article.

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