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Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.
de la Paz Santangelo M, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R, Lenaerts AJ, Schnappinger D, Therisod M, Ehrt S, Sygusch J, Jackson M. de la Paz Santangelo M, et al. Among authors: jackson m. J Biol Chem. 2011 Nov 18;286(46):40219-31. doi: 10.1074/jbc.M111.259440. Epub 2011 Sep 23. J Biol Chem. 2011. PMID: 21949126 Free PMC article.
The cell envelope glycoconjugates of Mycobacterium tuberculosis.
Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M. Angala SK, et al. Among authors: jackson m. Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Crit Rev Biochem Mol Biol. 2014. PMID: 24915502 Free PMC article. Review.
2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.
Jeon AB, Obregón-Henao A, Ackart DF, Podell BK, Belardinelli JM, Jackson M, Nguyen TV, Blackledge MS, Melander RJ, Melander C, Johnson BK, Abramovitch RB, Basaraba RJ. Jeon AB, et al. Among authors: jackson m. PLoS One. 2017 Jul 27;12(7):e0180925. doi: 10.1371/journal.pone.0180925. eCollection 2017. PLoS One. 2017. PMID: 28749949 Free PMC article.
Direct Inhibition of MmpL3 by Novel Antitubercular Compounds.
Li W, Stevens CM, Pandya AN, Darzynkiewicz Z, Bhattarai P, Tong W, Gonzalez-Juarrero M, North EJ, Zgurskaya HI, Jackson M. Li W, et al. Among authors: jackson m. ACS Infect Dis. 2019 Jun 14;5(6):1001-1012. doi: 10.1021/acsinfecdis.9b00048. Epub 2019 Mar 28. ACS Infect Dis. 2019. PMID: 30882198 Free PMC article.
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
Thomas SE, Whitehouse AJ, Brown K, Burbaud S, Belardinelli JM, Sangen J, Lahiri R, Libardo MDJ, Gupta P, Malhotra S, Boshoff HIM, Jackson M, Abell C, Coyne AG, Blundell TL, Floto RA, Mendes V. Thomas SE, et al. Among authors: jackson m. Nucleic Acids Res. 2020 Aug 20;48(14):8099-8112. doi: 10.1093/nar/gkaa539. Nucleic Acids Res. 2020. PMID: 32602532 Free PMC article.
5,030 results