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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
Nature. 2016 Jun 16;534(7607):396-401. doi: 10.1038/nature18300. Epub 2016 Jun 1.
Nature. 2016.
PMID: 27281205
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
Sahin U, Oehm P, Derhovanessian E, Jabulowsky RA, Vormehr M, Gold M, Maurus D, Schwarck-Kokarakis D, Kuhn AN, Omokoko T, Kranz LM, Diken M, Kreiter S, Haas H, Attig S, Rae R, Cuk K, Kemmer-Brück A, Breitkreuz A, Tolliver C, Caspar J, Quinkhardt J, Hebich L, Stein M, Hohberger A, Vogler I, Liebig I, Renken S, Sikorski J, Leierer M, Müller V, Mitzel-Rink H, Miederer M, Huber C, Grabbe S, Utikal J, Pinter A, Kaufmann R, Hassel JC, Loquai C, Türeci Ö.
Sahin U, et al. Among authors: jabulowsky ra.
Nature. 2020 Sep;585(7823):107-112. doi: 10.1038/s41586-020-2537-9. Epub 2020 Jul 29.
Nature. 2020.
PMID: 32728218
Clinical Trial.
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Cancer immunotherapy achieves breakthrough status: 12th annual meeting of the association for cancer immunotherapy (CIMT), Mainz, Germany, May 6-8, 2014.
Kloke BP, Mahr A, Jabulowsky RA, Kutscher S, Rae R, Britten CM.
Kloke BP, et al. Among authors: jabulowsky ra.
Cancer Immunol Immunother. 2015 Jul;64(7):923-30. doi: 10.1007/s00262-014-1643-7. Epub 2014 Dec 30.
Cancer Immunol Immunother. 2015.
PMID: 25548093
Free PMC article.
No abstract available.
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Antigen-specific oncolytic MV-based tumor vaccines through presentation of selected tumor-associated antigens on infected cells or virus-like particles.
Hutzler S, Erbar S, Jabulowsky RA, Hanauer JRH, Schnotz JH, Beissert T, Bodmer BS, Eberle R, Boller K, Klamp T, Sahin U, Mühlebach MD.
Hutzler S, et al. Among authors: jabulowsky ra.
Sci Rep. 2017 Dec 4;7(1):16892. doi: 10.1038/s41598-017-16928-8.
Sci Rep. 2017.
PMID: 29203786
Free PMC article.
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EGFR-targeted granzyme B expressed in NK cells enhances natural cytotoxicity and mediates specific killing of tumor cells.
Oberoi P, Jabulowsky RA, Bähr-Mahmud H, Wels WS.
Oberoi P, et al. Among authors: jabulowsky ra.
PLoS One. 2013;8(4):e61267. doi: 10.1371/journal.pone.0061267. Epub 2013 Apr 3.
PLoS One. 2013.
PMID: 23573299
Free PMC article.
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Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein.
Dälken B, Jabulowsky RA, Oberoi P, Benhar I, Wels WS.
Dälken B, et al. Among authors: jabulowsky ra.
PLoS One. 2010 Dec 22;5(12):e14404. doi: 10.1371/journal.pone.0014404.
PLoS One. 2010.
PMID: 21203542
Free PMC article.
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Surface charge-modification prevents sequestration and enhances tumor-cell specificity of a recombinant granzyme B-TGFα fusion protein.
Jabulowsky RA, Oberoi P, Bähr-Mahmud H, Dälken B, Wels WS.
Jabulowsky RA, et al.
Bioconjug Chem. 2012 Aug 15;23(8):1567-76. doi: 10.1021/bc3000657. Epub 2012 Jul 16.
Bioconjug Chem. 2012.
PMID: 22759275
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Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity.
Horn AV, Klawitter S, Held U, Berger A, Vasudevan AA, Bock A, Hofmann H, Hanschmann KM, Trösemeier JH, Flory E, Jabulowsky RA, Han JS, Löwer J, Löwer R, Münk C, Schumann GG.
Horn AV, et al. Among authors: jabulowsky ra.
Nucleic Acids Res. 2014 Jan;42(1):396-416. doi: 10.1093/nar/gkt898. Epub 2013 Oct 7.
Nucleic Acids Res. 2014.
PMID: 24101588
Free PMC article.
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