Jørgensen PT - Search Results

1

Carbazole modified oligonucleotides: synthesis, hybridization studies and fluorescence properties.

Gouda AS, Przypis Ł, Walczak K, Jørgensen PT, Wengel J. Gouda AS, et al. Among authors: jorgensen pt. Org Biomol Chem. 2020 Sep 21;18(35):6935-6948. doi: 10.1039/d0ob01553a. Epub 2020 Sep 2. Org Biomol Chem. 2020. PMID: 32936176

2

Using an aryl phenanthroimidazole moiety as a conjugated flexible intercalator to improve the hybridization efficiency of a triplex-forming oligonucleotide.

Osman AM, Jørgensen PT, Bomholt N, Pedersen EB. Osman AM, et al. Among authors: jorgensen pt. Bioorg Med Chem. 2008 Dec 1;16(23):9937-47. doi: 10.1016/j.bmc.2008.10.037. Epub 2008 Oct 17. Bioorg Med Chem. 2008. PMID: 18977149

3

Synthesis of locked pyranosyl nucleic acid (LpNA).

Bomholt N, Jørgensen PT, Pedersen EB. Bomholt N, et al. Among authors: jorgensen pt. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7376-8. doi: 10.1016/j.bmcl.2011.10.005. Epub 2011 Oct 8. Bioorg Med Chem Lett. 2011. PMID: 22041061

4

Conjugation of a 3-(1H-phenanthro[9,10-d]imidazol-2-yl)-1H-indole intercalator to a triplex oligonucleotide and to a three-way junction.

Fatthalla MI, Elkholy YM, Abbas NS, Mandour AH, Jørgensen PT, Bomholt N, Pedersen EB. Fatthalla MI, et al. Among authors: jorgensen pt. Bioorg Med Chem. 2012 Jan 1;20(1):207-14. doi: 10.1016/j.bmc.2011.11.013. Epub 2011 Nov 13. Bioorg Med Chem. 2012. PMID: 22154560

5

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Moreno PM, et al. Among authors: jorgensen pt. Nucleic Acids Res. 2013 Mar 1;41(5):3257-73. doi: 10.1093/nar/gkt007. Epub 2013 Jan 23. Nucleic Acids Res. 2013. PMID: 23345620 Free PMC article.

6

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Geny S, Moreno PM, Krzywkowski T, Gissberg O, Andersen NK, Isse AJ, El-Madani AM, Lou C, Pabon YV, Anderson BA, Zaghloul EM, Zain R, Hrdlicka PJ, Jørgensen PT, Nilsson M, Lundin KE, Pedersen EB, Wengel J, Smith CI. Geny S, et al. Among authors: jorgensen pt. Nucleic Acids Res. 2016 Mar 18;44(5):2007-19. doi: 10.1093/nar/gkw021. Epub 2016 Feb 8. Nucleic Acids Res. 2016. PMID: 26857548 Free PMC article.

7

Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA, and 2'-Amino-LNA Monomers.

Ries A, Kumar R, Lou C, Kosbar T, Vengut-Climent E, Jørgensen PT, Morales JC, Wengel J. Ries A, et al. Among authors: jorgensen pt. J Org Chem. 2016 Nov 18;81(22):10845-10856. doi: 10.1021/acs.joc.6b01917. Epub 2016 Oct 25. J Org Chem. 2016. PMID: 27736097

8

Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule.

Aaldering LJ, Poongavanam V, Langkjaer N, Murugan NA, Jørgensen PT, Wengel J, Veedu RN. Aaldering LJ, et al. Among authors: jorgensen pt. Chembiochem. 2017 Apr 18;18(8):755-763. doi: 10.1002/cbic.201600654. Epub 2017 Mar 15. Chembiochem. 2017. PMID: 28150905 Free PMC article.

9

LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures.

Pabon-Martinez YV, Xu Y, Villa A, Lundin KE, Geny S, Nguyen CH, Pedersen EB, Jørgensen PT, Wengel J, Nilsson L, Smith CIE, Zain R. Pabon-Martinez YV, et al. Among authors: jorgensen pt. Sci Rep. 2017 Sep 8;7(1):11043. doi: 10.1038/s41598-017-09147-8. Sci Rep. 2017. PMID: 28887512 Free PMC article.

10

microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation.

Moura J, Sørensen A, Leal EC, Svendsen R, Carvalho L, Willemoes RJ, Jørgensen PT, Jenssen H, Wengel J, Dalgaard LT, Carvalho E. Moura J, et al. Among authors: jorgensen pt. Sci Rep. 2019 Apr 9;9(1):5836. doi: 10.1038/s41598-019-42309-4. Sci Rep. 2019. PMID: 30967591 Free PMC article.

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