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Neuromodulatory effect of Gαs- or Gαq-coupled G-protein-coupled receptor on NMDA receptor selectively activates the NMDA receptor/Ca2+/calcineurin/cAMP response element-binding protein-regulated transcriptional coactivator 1 pathway to effectively induce brain-derived neurotrophic factor expression in neurons.
Fukuchi M, Tabuchi A, Kuwana Y, Watanabe S, Inoue M, Takasaki I, Izumi H, Tanaka A, Inoue R, Mori H, Komatsu H, Takemori H, Okuno H, Bito H, Tsuda M. Fukuchi M, et al. Among authors: izumi h. J Neurosci. 2015 Apr 8;35(14):5606-24. doi: 10.1523/JNEUROSCI.3650-14.2015. J Neurosci. 2015. PMID: 25855176 Free PMC article.
TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
Miyao N, Hata Y, Izumi H, Nagaoka R, Oku Y, Takasaki I, Ishikawa T, Takarada S, Okabe M, Nakaoka H, Ibuki K, Ozawa S, Yoshida T, Hasegawa H, Makita N, Nishida N, Mori H, Ichida F, Hirono K. Miyao N, et al. Among authors: izumi h. PLoS One. 2020 Apr 1;15(4):e0227393. doi: 10.1371/journal.pone.0227393. eCollection 2020. PLoS One. 2020. PMID: 32236096 Free PMC article.
1,019 results