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Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Yoshida T, Yamagata A, Imai A, Kim J, Izumi H, Nakashima S, Shiroshima T, Maeda A, Iwasawa-Okamoto S, Azechi K, Osaka F, Saitoh T, Maenaka K, Shimada T, Fukata Y, Fukata M, Matsumoto J, Nishijo H, Takao K, Tanaka S, Okabe S, Tabuchi K, Uemura T, Mishina M, Mori H, Fukai S. Yoshida T, et al. Among authors: izumi h. Nat Commun. 2021 Mar 23;12(1):1848. doi: 10.1038/s41467-021-22059-6. Nat Commun. 2021. PMID: 33758193 Free PMC article.
Neuromodulatory effect of Gαs- or Gαq-coupled G-protein-coupled receptor on NMDA receptor selectively activates the NMDA receptor/Ca2+/calcineurin/cAMP response element-binding protein-regulated transcriptional coactivator 1 pathway to effectively induce brain-derived neurotrophic factor expression in neurons.
Fukuchi M, Tabuchi A, Kuwana Y, Watanabe S, Inoue M, Takasaki I, Izumi H, Tanaka A, Inoue R, Mori H, Komatsu H, Takemori H, Okuno H, Bito H, Tsuda M. Fukuchi M, et al. Among authors: izumi h. J Neurosci. 2015 Apr 8;35(14):5606-24. doi: 10.1523/JNEUROSCI.3650-14.2015. J Neurosci. 2015. PMID: 25855176 Free PMC article.
A novel serine racemase inhibitor suppresses neuronal over-activation in vivo.
Mori H, Wada R, Takahara S, Horino Y, Izumi H, Ishimoto T, Yoshida T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N. Mori H, et al. Among authors: izumi h. Bioorg Med Chem. 2017 Jul 15;25(14):3736-3745. doi: 10.1016/j.bmc.2017.05.011. Epub 2017 May 11. Bioorg Med Chem. 2017. PMID: 28533113
TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
Miyao N, Hata Y, Izumi H, Nagaoka R, Oku Y, Takasaki I, Ishikawa T, Takarada S, Okabe M, Nakaoka H, Ibuki K, Ozawa S, Yoshida T, Hasegawa H, Makita N, Nishida N, Mori H, Ichida F, Hirono K. Miyao N, et al. Among authors: izumi h. PLoS One. 2020 Apr 1;15(4):e0227393. doi: 10.1371/journal.pone.0227393. eCollection 2020. PLoS One. 2020. PMID: 32236096 Free PMC article.
1,016 results