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A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Maruggi G, Mallett CP, Westerbeck JW, Chen T, Lofano G, Friedrich K, Qu L, Sun JT, McAuliffe J, Kanitkar A, Arrildt KT, Wang KF, McBee I, McCoy D, Terry R, Rowles A, Abrahim MA, Ringenberg MA, Gains MJ, Spickler C, Xie X, Zou J, Shi PY, Dutt T, Henao-Tamayo M, Ragan I, Bowen RA, Johnson R, Nuti S, Luisi K, Ulmer JB, Steff AM, Jalah R, Bertholet S, Stokes AH, Yu D. Maruggi G, et al. Among authors: ragan i. Mol Ther. 2022 May 4;30(5):1897-1912. doi: 10.1016/j.ymthe.2022.01.001. Epub 2022 Jan 3. Mol Ther. 2022. PMID: 34990810 Free PMC article. Clinical Trial.
Preliminary Evaluation of a Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Providing Full Protection against Heterologous Virulent Challenge in Cattle.
Wilson WC, Faburay B, Trujillo JD, Ragan I, Sunwoo SY, Morozov I, Shivanna V, Balogh A, Urbaniak K, McVey DS, Bold D, Gaudreault NN, Schirtzinger EE, Ma W, Richt JA. Wilson WC, et al. Among authors: ragan i. Vaccines (Basel). 2021 Jul 6;9(7):748. doi: 10.3390/vaccines9070748. Vaccines (Basel). 2021. PMID: 34358166 Free PMC article.
A Whole Virion Vaccine for COVID-19 Produced via a Novel Inactivation Method and Preliminary Demonstration of Efficacy in an Animal Challenge Model.
Ragan IK, Hartson LM, Dutt TS, Obregon-Henao A, Maison RM, Gordy P, Fox A, Karger BR, Cross ST, Kapuscinski ML, Cooper SK, Podell BK, Stenglein MD, Bowen RA, Henao-Tamayo M, Goodrich RP. Ragan IK, et al. Vaccines (Basel). 2021 Apr 1;9(4):340. doi: 10.3390/vaccines9040340. Vaccines (Basel). 2021. PMID: 33916180 Free PMC article.
18 results