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An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: iwakura y. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation.
Ito Y, Sasaki T, Li Y, Tanoue T, Sugiura Y, Skelly AN, Suda W, Kawashima Y, Okahashi N, Watanabe E, Horikawa H, Shiohama A, Kurokawa R, Kawakami E, Iseki H, Kawasaki H, Iwakura Y, Shiota A, Yu L, Hisatsune J, Koseki H, Sugai M, Arita M, Ohara O, Matsui T, Suematsu M, Hattori M, Atarashi K, Amagai M, Honda K. Ito Y, et al. Among authors: iwakura y. Cell Rep. 2021 Apr 27;35(4):109052. doi: 10.1016/j.celrep.2021.109052. Cell Rep. 2021. PMID: 33910010 Free article.
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities.
Lee C, Verma R, Byun S, Jeun EJ, Kim GC, Lee S, Kang HJ, Kim CJ, Sharma G, Lahiri A, Paul S, Kim KS, Hwang DS, Iwakura Y, Speciale I, Molinaro A, De Castro C, Rudra D, Im SH. Lee C, et al. Among authors: iwakura y. Nat Commun. 2021 Jun 14;12(1):3611. doi: 10.1038/s41467-021-23929-9. Nat Commun. 2021. PMID: 34127673 Free PMC article.
Arthritis flares mediated by tissue-resident memory T cells in the joint.
Chang MH, Levescot A, Nelson-Maney N, Blaustein RB, Winden KD, Morris A, Wactor A, Balu S, Grieshaber-Bouyer R, Wei K, Henderson LA, Iwakura Y, Clark RA, Rao DA, Fuhlbrigge RC, Nigrovic PA. Chang MH, et al. Among authors: iwakura y. Cell Rep. 2021 Oct 26;37(4):109902. doi: 10.1016/j.celrep.2021.109902. Cell Rep. 2021. PMID: 34706228 Free PMC article.
Dectin-1 and Dectin-2 in innate immunity against fungi.
Saijo S, Iwakura Y. Saijo S, et al. Among authors: iwakura y. Int Immunol. 2011 Aug;23(8):467-72. doi: 10.1093/intimm/dxr046. Epub 2011 Jun 15. Int Immunol. 2011. PMID: 21677049 Review.
788 results