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Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex.
Mathieu E , Bernard AS , Quévrain E , Zoumpoulaki M , Iriart S , Lung-Soong C , Lai B , Medjoubi K , Henry L , Nagarajan S , Poyer F , Scheitler A , Ivanović-Burmazović I , Marco S , Somogyi A , Seksik P , Delsuc N , Policar C . Mathieu E , et al. Chem Commun (Camb). 2020 Jul 21;56(57):7885-7888. doi: 10.1039/d0cc03398g. Epub 2020 Jun 10. Chem Commun (Camb). 2020. PMID: 32520039 Free article.
Quinol-containing ligands enable high superoxide dismutase activity by modulating coordination number, charge, oxidation states and stability of manganese complexes throughout redox cycling.
Senft L, Moore JL, Franke A, Fisher KR, Scheitler A, Zahl A, Puchta R, Fehn D, Ison S, Sader S, Ivanović-Burmazović I, Goldsmith CR. Senft L, et al. Chem Sci. 2021 Jul 13;12(31):10483-10500. doi: 10.1039/d1sc02465e. eCollection 2021 Aug 11. Chem Sci. 2021. PMID: 34447541 Free PMC article.
Diquinol Functionality Boosts the Superoxide Dismutase Mimicry of a Zn(II) Complex with a Redox-Active Ligand while Maintaining Catalyst Stability and Enhanced Activity in Phosphate Solution.
Moore JL, Oppelt J, Senft L, Franke A, Scheitler A, Dukes MW, Alix HB, Saunders AC, Karbalaei S, Schwartz DD, Ivanović-Burmazović I, Goldsmith CR. Moore JL, et al. Among authors: ivanovic burmazovic i. Inorg Chem. 2022 Dec 12;61(49):19983-19997. doi: 10.1021/acs.inorgchem.2c03256. Epub 2022 Nov 29. Inorg Chem. 2022. PMID: 36445832
128 results