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261 results

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Page 1
Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma.
Carotenuto P, Romano A, Barbato A, Quadrano P, Brillante S, Volpe M, Ferrante L, Tammaro R, Morleo M, De Cegli R, Iuliano A, Testa M, Andreone F, Ciliberto G, Clery E, Troncone G, Palma G, Arra C, Barbieri A, Capone M, Madonna G, Ascierto PA, Lanfrancone L, Indrieri A, Franco B. Carotenuto P, et al. Among authors: iuliano a. Cell Rep. 2022 Nov 8;41(6):111601. doi: 10.1016/j.celrep.2022.111601. Cell Rep. 2022. PMID: 36351409 Free article.
Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.
Mottini C, Tomihara H, Carrella D, Lamolinara A, Iezzi M, Huang JK, Amoreo CA, Buglioni S, Manni I, Robinson FS, Minelli R, Kang Y, Fleming JB, Kim MP, Bristow CA, Trisciuoglio D, Iuliano A, Del Bufalo D, Di Bernardo D, Melisi D, Draetta GF, Ciliberto G, Carugo A, Cardone L. Mottini C, et al. Among authors: iuliano a. Cancer Res. 2019 Nov 1;79(21):5612-5625. doi: 10.1158/0008-5472.CAN-19-0187. Epub 2019 Sep 5. Cancer Res. 2019. PMID: 31492820
Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma.
Barbato A, Iuliano A, Volpe M, D'Alterio R, Brillante S, Massa F, De Cegli R, Carrella S, Salati M, Russo A, Russo G, Riccardo S, Cacchiarelli D, Capone M, Madonna G, Ascierto PA, Franco B, Indrieri A, Carotenuto P. Barbato A, et al. Among authors: iuliano a. Int J Mol Sci. 2021 Feb 11;22(4):1801. doi: 10.3390/ijms22041801. Int J Mol Sci. 2021. PMID: 33670365 Free PMC article.
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers.
Barbato A, Piscopo F, Salati M, Pollastro C, Evangelista L, Ferrante L, Limongello D, Brillante S, Iuliano A, Reggiani-Bonetti L, Salatiello M, Iaccarino A, Pisapia P, Malapelle U, Troncone G, Indrieri A, Dominici M, Franco B, Carotenuto P. Barbato A, et al. Among authors: iuliano a. Clin Exp Med. 2024 Apr 10;24(1):74. doi: 10.1007/s10238-024-01332-0. Clin Exp Med. 2024. PMID: 38598008 Free PMC article.
Automatic identification of small molecules that promote cell conversion and reprogramming.
Napolitano F, Rapakoulia T, Annunziata P, Hasegawa A, Cardon M, Napolitano S, Vaccaro L, Iuliano A, Wanderlingh LG, Kasukawa T, Medina DL, Cacchiarelli D, Gao X, di Bernardo D, Arner E. Napolitano F, et al. Among authors: iuliano a. Stem Cell Reports. 2021 May 11;16(5):1381-1390. doi: 10.1016/j.stemcr.2021.03.028. Epub 2021 Apr 22. Stem Cell Reports. 2021. PMID: 33891873 Free PMC article.
MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis.
Candiello E, Reato G, Verginelli F, Gambardella G, D Ambrosio A, Calandra N, Orzan F, Iuliano A, Albano R, Sassi F, Luraghi P, Comoglio PM, Bertotti A, Trusolino L, Boccaccio C. Candiello E, et al. Among authors: iuliano a. Mol Oncol. 2023 Jul;17(7):1280-1301. doi: 10.1002/1878-0261.13408. Epub 2023 Mar 19. Mol Oncol. 2023. PMID: 36862005 Free PMC article.
Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia.
Sambri I, Massa F, Gullo F, Meneghini S, Cassina L, Carraro M, Dina G, Quattrini A, Patanella L, Carissimo A, Iuliano A, Santorelli F, Codazzi F, Grohovaz F, Bernardi P, Becchetti A, Casari G. Sambri I, et al. Among authors: iuliano a. EBioMedicine. 2020 Nov;61:103050. doi: 10.1016/j.ebiom.2020.103050. Epub 2020 Oct 9. EBioMedicine. 2020. PMID: 33045469 Free PMC article.
Liver gene therapy with intein-mediated F8 trans-splicing corrects mouse haemophilia A.
Esposito F, Lyubenova H, Tornabene P, Auricchio S, Iuliano A, Nusco E, Merlin S, Olgasi C, Manni G, Gargaro M, Fallarino F, Follenzi A, Auricchio A. Esposito F, et al. Among authors: iuliano a. EMBO Mol Med. 2022 Jun 8;14(6):e15199. doi: 10.15252/emmm.202115199. Epub 2022 May 2. EMBO Mol Med. 2022. PMID: 35491676 Free PMC article.
Therapeutic homology-independent targeted integration in retina and liver.
Tornabene P, Ferla R, Llado-Santaeularia M, Centrulo M, Dell'Anno M, Esposito F, Marrocco E, Pone E, Minopoli R, Iodice C, Nusco E, Rossi S, Lyubenova H, Manfredi A, Di Filippo L, Iuliano A, Torella A, Piluso G, Musacchia F, Surace EM, Cacchiarelli D, Nigro V, Auricchio A. Tornabene P, et al. Among authors: iuliano a. Nat Commun. 2022 Apr 12;13(1):1963. doi: 10.1038/s41467-022-29550-8. Nat Commun. 2022. PMID: 35414130 Free PMC article.
A pilot clinical trial with losartan in Myhre syndrome.
Cappuccio G, Caiazza M, Roca A, Melis D, Iuliano A, Matyas G, Rubino M, Limongelli G, Brunetti-Pierri N. Cappuccio G, et al. Among authors: iuliano a. Am J Med Genet A. 2021 Mar;185(3):702-709. doi: 10.1002/ajmg.a.62019. Epub 2020 Dec 24. Am J Med Genet A. 2021. PMID: 33369056 Free PMC article. Clinical Trial.
261 results