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PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers.
Aakula A, Isomursu A, Rupp C, Erickson A, Gupta N, Kauko O, Shah P, Padzik A, Pokharel YR, Kaur A, Li SP, Trotman L, Taimen P, Rannikko A, Lammerding J, Paatero I, Mirtti T, Ivaska J, Westermarck J. Aakula A, et al. Among authors: isomursu a. Mol Oncol. 2023 Jun;17(6):1007-1023. doi: 10.1002/1878-0261.13353. Epub 2023 Apr 18. Mol Oncol. 2023. PMID: 36461911 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34005208
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling.
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani Nia F, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp HJ, Lappalainen P, Ivaska J. Salomaa SI, et al. Among authors: isomursu a. Curr Biol. 2021 Nov 22;31(22):4956-4970.e9. doi: 10.1016/j.cub.2021.09.022. Epub 2021 Oct 4. Curr Biol. 2021. PMID: 34610274 Free article.
Directed cell migration towards softer environments.
Isomursu A, Park KY, Hou J, Cheng B, Mathieu M, Shamsan GA, Fuller B, Kasim J, Mahmoodi MM, Lu TJ, Genin GM, Xu F, Lin M, Distefano MD, Ivaska J, Odde DJ. Isomursu A, et al. Nat Mater. 2022 Sep;21(9):1081-1090. doi: 10.1038/s41563-022-01294-2. Epub 2022 Jul 11. Nat Mater. 2022. PMID: 35817964 Free PMC article.
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries.
Peuhu E, Jacquemet G, Scheele CLGJ, Isomursu A, Laisne MC, Koskinen LM, Paatero I, Thol K, Georgiadou M, Guzmán C, Koskinen S, Laiho A, Elo LL, Boström P, Hartiala P, van Rheenen J, Ivaska J. Peuhu E, et al. Among authors: isomursu a. Dev Cell. 2022 Oct 24;57(20):2350-2364.e7. doi: 10.1016/j.devcel.2022.09.016. Dev Cell. 2022. PMID: 36283390 Free article.
14 results