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Potent and biostable inhibitors of the main protease of SARS-CoV-2.
Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Azuma C, Nakayama M, Onishi T, Nakano H, Wada N, Hori M, Shinohara K, Miura Y, Kawada T, Hayashi H, Hattori SI, Bulut H, Das D, Takamune N, Kishimoto N, Saruwatari J, Okamura T, Nakano K, Misumi S, Mitsuya H, Tamamura H. Tsuji K, et al. Among authors: ishii t. iScience. 2022 Nov 18;25(11):105365. doi: 10.1016/j.isci.2022.105365. Epub 2022 Nov 1. iScience. 2022. PMID: 36338434 Free PMC article.
A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators.
Matsuda K, Kobayakawa T, Kariya R, Tsuchiya K, Ryu S, Tsuji K, Ishii T, Gatanaga H, Yoshimura K, Okada S, Hamada A, Mitsuya H, Tamamura H, Maeda K. Matsuda K, et al. Among authors: ishii t. Front Microbiol. 2021 Mar 17;12:636276. doi: 10.3389/fmicb.2021.636276. eCollection 2021. Front Microbiol. 2021. PMID: 33815322 Free PMC article.
Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins.
Kobayakawa T, Yokoyama M, Tsuji K, Fujino M, Kurakami M, Onishi T, Boku S, Ishii T, Miura Y, Shinohara K, Kishihara Y, Ohashi N, Kotani O, Murakami T, Sato H, Tamamura H. Kobayakawa T, et al. Among authors: ishii t. RSC Adv. 2023 Jan 12;13(3):2156-2167. doi: 10.1039/d2ra06837k. eCollection 2023 Jan 6. RSC Adv. 2023. PMID: 36712613 Free PMC article.
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: ishii t. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Development of anti-HBV agents targeting HBV capsid proteins.
Kobayakawa T, Amano M, Nakayama M, Tsuji K, Ishii T, Miura Y, Shinohara K, Yamamoto K, Matsuoka M, Tamamura H. Kobayakawa T, et al. Among authors: ishii t. RSC Med Chem. 2023 Aug 24;14(10):1973-1980. doi: 10.1039/d3md00258f. eCollection 2023 Oct 18. RSC Med Chem. 2023. PMID: 37859721
4,359 results