Irving AJ - Search Results

1

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology.

Morales P, Whyte LS, Chicharro R, Gómez-Cañas M, Pazos MR, Goya P, Irving AJ, Fernández-Ruiz J, Ross RA, Jagerovic N. Morales P, et al. Among authors: irving aj. J Med Chem. 2016 Mar 10;59(5):1840-53. doi: 10.1021/acs.jmedchem.5b01331. Epub 2016 Feb 5. J Med Chem. 2016. PMID: 26789378

2

Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.

Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C. Moreno E, et al. Among authors: irving aj. J Biol Chem. 2014 Aug 8;289(32):21960-72. doi: 10.1074/jbc.M114.561761. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942731 Free PMC article.

3

Modulation of l-α-lysophosphatidylinositol/GPR55 MAP kinase signalling by CB2 receptor agonists: identifying novel GPR55 inhibitors.

Anavi-Goffer S, Irving AJ, Ross RA. Anavi-Goffer S, et al. Among authors: irving aj. J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):303-10. doi: 10.1515/jbcpp-2015-0142. J Basic Clin Physiol Pharmacol. 2016. PMID: 27089417 Free article.

4

Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids.

Anavi-Goffer S, Baillie G, Irving AJ, Gertsch J, Greig IR, Pertwee RG, Ross RA. Anavi-Goffer S, et al. Among authors: irving aj. J Biol Chem. 2012 Jan 2;287(1):91-104. doi: 10.1074/jbc.M111.296020. Epub 2011 Oct 25. J Biol Chem. 2012. PMID: 22027819 Free PMC article.

5

A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells.

Ford LA, Roelofs AJ, Anavi-Goffer S, Mowat L, Simpson DG, Irving AJ, Rogers MJ, Rajnicek AM, Ross RA. Ford LA, et al. Among authors: irving aj. Br J Pharmacol. 2010 Jun;160(3):762-71. doi: 10.1111/j.1476-5381.2010.00743.x. Br J Pharmacol. 2010. PMID: 20590578 Free PMC article.

6

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists.

Yrjölä S, Parkkari T, Navia-Paldanius D, Laitinen T, Kaczor AA, Kokkola T, Adusei-Mensah F, Savinainen JR, Laitinen JT, Poso A, Alexander A, Penman J, Stott L, Anskat M, Irving AJ, Nevalainen TJ. Yrjölä S, et al. Among authors: irving aj. Eur J Med Chem. 2016 Jan 1;107:119-32. doi: 10.1016/j.ejmech.2015.10.050. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26575458

7

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation.

Henstridge CM, Balenga NA, Ford LA, Ross RA, Waldhoer M, Irving AJ. Henstridge CM, et al. Among authors: irving aj. FASEB J. 2009 Jan;23(1):183-93. doi: 10.1096/fj.08-108670. Epub 2008 Aug 29. FASEB J. 2009. PMID: 18757503

8

Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries.

Daly CJ, Ross RA, Whyte J, Henstridge CM, Irving AJ, McGrath JC. Daly CJ, et al. Among authors: irving aj. Br J Pharmacol. 2010 Feb;159(4):787-96. doi: 10.1111/j.1476-5381.2009.00608.x. Epub 2010 Feb 5. Br J Pharmacol. 2010. PMID: 20136833 Free PMC article.

9

GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?

Nevalainen T, Irving AJ. Nevalainen T, et al. Among authors: irving aj. Curr Top Med Chem. 2010;10(8):799-813. doi: 10.2174/156802610791164229. Curr Top Med Chem. 2010. PMID: 20370712 Review.

10

Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception.

Ross RA, Coutts AA, McFarlane SM, Anavi-Goffer S, Irving AJ, Pertwee RG, MacEwan DJ, Scott RH. Ross RA, et al. Among authors: irving aj. Neuropharmacology. 2001;40(2):221-32. doi: 10.1016/s0028-3908(00)00135-0. Neuropharmacology. 2001. PMID: 11114401

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