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Page 1
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. Among authors: irondelle m. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease.
Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C. Pandiani C, et al. Among authors: irondelle m. Cell Death Differ. 2021 Jun;28(6):1990-2000. doi: 10.1038/s41418-020-00730-7. Epub 2021 Jan 18. Cell Death Differ. 2021. PMID: 33462406 Free PMC article.
Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion.
Guilbaud E, Barouillet T, Ilie M, Borowczyk C, Ivanov S, Sarrazy V, Vaillant N, Ayrault M, Castiglione A, Rignol G, Brest P, Bazioti V, Zaitsev K, Lebrigand K, Dussaud S, Magnone V, Bertolotto C, Marchetti S, Irondelle M, Goldberg I, Huby T, Westerterp M, Gautier EL, Mari B, Barbry P, Hofman P, Yvan-Charvet L. Guilbaud E, et al. Among authors: irondelle m. Cell Stem Cell. 2023 Jun 1;30(6):800-817.e9. doi: 10.1016/j.stem.2023.05.005. Cell Stem Cell. 2023. PMID: 37267915
Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC.
Meyenberg Cunha-de Padua M, Fabbri L, Dufies M, Lacas-Gervais S, Contenti J, Voyton C, Fazio S, Irondelle M, Mograbi B, Rouleau M, Sadaghianloo N, Rovini A, Brenner C, Craigen WJ, Bourgeais J, Herault O, Bost F, Mazure NM. Meyenberg Cunha-de Padua M, et al. Among authors: irondelle m. Cancers (Basel). 2020 Nov 23;12(11):3484. doi: 10.3390/cancers12113484. Cancers (Basel). 2020. PMID: 33238609 Free PMC article.
Blockade of the pro-fibrotic reaction mediated by the miR-143/-145 cluster enhances the responses to targeted therapy in melanoma.
Diazzi S, Baeri A, Fassy J, Lecacheur M, Marin-Bejar O, Girard CA, Lefevre L, Lacoux C, Irondelle M, Mounier C, Truchi M, Couralet M, Ohanna M, Carminati A, Berestjuk I, Larbret F, Gilot D, Vassaux G, Marine JC, Deckert M, Mari B, Tartare-Deckert S. Diazzi S, et al. Among authors: irondelle m. EMBO Mol Med. 2022 Mar 7;14(3):e15295. doi: 10.15252/emmm.202115295. Epub 2022 Feb 14. EMBO Mol Med. 2022. PMID: 35156321 Free PMC article.
UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling.
Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, Dagnino S, Uhler J, Irondelle M, Gay AS, Fleuriot L, Debayle D, Lacas-Gervais S, Cormont M, Bertero T, Bost F, Gilleron J, Clavel S. Torrino S, et al. Among authors: irondelle m. Elife. 2021 Apr 22;10:e68348. doi: 10.7554/eLife.68348. Elife. 2021. PMID: 33884955 Free PMC article.
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells.
Rovera C, Berestjuk I, Lecacheur M, Tavernier C, Diazzi S, Pisano S, Irondelle M, Mallavialle A, Albrengues J, Gaggioli C, Girard CA, Passeron T, Deckert M, Tartare-Deckert S, Prod'homme V. Rovera C, et al. Among authors: irondelle m. Cancer Res. 2022 May 3;82(9):1774-1788. doi: 10.1158/0008-5472.CAN-21-0501. Cancer Res. 2022. PMID: 35502542 Free article.
Control of MT1-MMP transport by atypical PKC during breast-cancer progression.
Rossé C, Lodillinsky C, Fuhrmann L, Nourieh M, Monteiro P, Irondelle M, Lagoutte E, Vacher S, Waharte F, Paul-Gilloteaux P, Romao M, Sengmanivong L, Linch M, van Lint J, Raposo G, Vincent-Salomon A, Bièche I, Parker PJ, Chavrier P. Rossé C, et al. Among authors: irondelle m. Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1872-9. doi: 10.1073/pnas.1400749111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753582 Free PMC article.
25 results