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A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Pacini C, Duncan E, Gonçalves E, Gilbert J, Bhosle S, Horswell S, Karakoc E, Lightfoot H, Curry E, Muyas F, Bouaboula M, Pedamallu CS, Cortes-Ciriano I, Behan FM, Zalmas LP, Barthorpe A, Francies H, Rowley S, Pollard J, Beltrao P, Parts L, Iorio F, Garnett MJ. Pacini C, et al. Among authors: iorio f. Cancer Cell. 2024 Feb 12;42(2):301-316.e9. doi: 10.1016/j.ccell.2023.12.016. Epub 2024 Jan 11. Cancer Cell. 2024. PMID: 38215750 Free article.
RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity.
Angioni R, Bonfanti M, Caporale N, Sánchez-Rodríguez R, Munari F, Savino A, Pasqualato S, Buratto D, Pagani I, Bertoldi N, Zanon C, Ferrari P, Ricciardelli E, Putaggio C, Ghezzi S, Elli F, Rotta L, Scardua A, Weber J, Cecatiello V, Iorio F, Zonta F, Cattelan AM, Vicenzi E, Vannini A, Molon B, Villa CE, Viola A, Testa G. Angioni R, et al. Among authors: iorio f. Cell Rep Med. 2023 Nov 21;4(11):101266. doi: 10.1016/j.xcrm.2023.101266. Epub 2023 Nov 8. Cell Rep Med. 2023. PMID: 37944530 Free PMC article.
Highlights from the 1st European cancer dependency map symposium and workshop.
Trastulla L, Savino A, Beltrao P, Ciriano IC, Fenici P, Garnett MJ, Guerini I, Bigas NL, Mattaj I, Petsalaki E, Riva L, Tape CJ, Leeuwen JV, Sharma S, Vazquez F, Iorio F. Trastulla L, et al. Among authors: iorio f. FEBS Lett. 2023 Aug;597(15):1921-1927. doi: 10.1002/1873-3468.14699. Epub 2023 Jul 24. FEBS Lett. 2023. PMID: 37487655
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Falkai P, Völzke H, Dörr M, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. Among authors: iorio f. medRxiv [Preprint]. 2023 May 11:2023.05.10.23289788. doi: 10.1101/2023.05.10.23289788. medRxiv. 2023. PMID: 37214898 Free PMC article. Preprint.
180 results