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Year Number of Results
1897 3
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1905 1
1906 2
1907 1
1908 1
1911 1
1913 2
1916 5
1919 2
1920 1
1921 5
1923 2
1925 2
1926 3
1929 1
1930 1
1931 3
1934 2
1935 4
1936 2
1937 2
1938 9
1939 2
1940 2
1941 4
1942 4
1943 2
1944 1
1945 28
1946 60
1947 84
1948 91
1949 85
1950 120
1951 157
1952 137
1953 193
1954 258
1955 669
1956 911
1957 860
1958 788
1959 737
1960 783
1961 849
1962 1010
1963 1527
1964 2091
1965 1626
1966 1809
1967 2270
1968 2597
1969 2600
1970 2680
1971 3019
1972 3368
1973 3646
1974 4167
1975 4165
1976 4037
1977 3837
1978 4021
1979 4078
1980 4293
1981 4389
1982 4731
1983 4949
1984 5267
1985 5813
1986 5644
1987 5457
1988 5437
1989 5759
1990 6157
1991 6316
1992 6550
1993 6541
1994 6443
1995 6381
1996 6537
1997 6393
1998 6495
1999 6545
2000 6859
2001 7084
2002 6900
2003 6988
2004 7096
2005 7754
2006 8112
2007 8288
2008 8440
2009 8533
2010 8997
2011 9501
2012 10119
2013 10230
2014 10189
2015 10162
2016 9513
2017 9107
2018 9565
2019 9923
2020 10394
2021 10205
2022 9990
2023 8324
2024 3321

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Page 1
Showing results for indole a
Search for Inwole A instead (3 results)
Recent progress in biologically active indole hybrids: a mini review.
Mahmoud E, Hayallah AM, Kovacic S, Abdelhamid D, Abdel-Aziz M. Mahmoud E, et al. Pharmacol Rep. 2022 Aug;74(4):570-582. doi: 10.1007/s43440-022-00370-3. Epub 2022 May 20. Pharmacol Rep. 2022. PMID: 35594012 Review.
The indole moiety is one of the most widespread heterocycles found in both natural products and biological systems. ...Scientists are therefore interested in the synthesis of biologically active indole-based hybrids such as indole-coumarin, indole-chal …
The indole moiety is one of the most widespread heterocycles found in both natural products and biological systems. ...Scientists are …
A Mild Two-Step Synthesis of Structurally Valuable Indole-Fused Derivatives.
Chen S, Xia Y, Jin S, Lei H, You K, Deng GJ. Chen S, et al. J Org Chem. 2022 Mar 4;87(5):3212-3222. doi: 10.1021/acs.joc.1c02927. Epub 2022 Feb 12. J Org Chem. 2022. PMID: 35152695
In this work, cyclohexanone was used as the key bridge to connect the indole and phenothiazine frameworks to construct a structurally valuable indole-fused derivative. The present protocol achieved the cascade construction of multiple C-hetero bonds, affording a con …
In this work, cyclohexanone was used as the key bridge to connect the indole and phenothiazine frameworks to construct a structurally …
Synthetic strategies, SAR studies, and computer modeling of indole 2 and 3-carboxamides as the strong enzyme inhibitors: a review.
Chehardoli G, Bahmani A. Chehardoli G, et al. Mol Divers. 2021 Feb;25(1):535-550. doi: 10.1007/s11030-020-10061-x. Epub 2020 May 12. Mol Divers. 2021. PMID: 32394235 Free PMC article. Review.
Indole derivatives have been the focus of many researchers in the study of pharmaceutical compounds for many years. ...It is hoped that indole scaffolds will be tested in the future for maximum activity in pharmacological compounds....
Indole derivatives have been the focus of many researchers in the study of pharmaceutical compounds for many years. ...It is hoped th …
The enol tautomer of indole-3-pyruvic acid as a biological switch in stress responses.
Bartolini B, Corniello C, Sella A, Somma F, Politi V. Bartolini B, et al. Adv Exp Med Biol. 2003;527:601-8. doi: 10.1007/978-1-4615-0135-0_69. Adv Exp Med Biol. 2003. PMID: 15206779 Review.
Indole-3-pyruvic acid (IPA) undergoes in solutions to the keto-enol tautomerism, which appears responsible of its pharmacological effects, as only the enol tautomer is an easy target for oxygen free-radicals and can be transformed directly to kynurenic acid (KYNA). ...
Indole-3-pyruvic acid (IPA) undergoes in solutions to the keto-enol tautomerism, which appears responsible of its pharmacological eff …
The indole pulse: a new perspective on indole signalling in Escherichia coli.
Gaimster H, Cama J, Hernández-Ainsa S, Keyser UF, Summers DK. Gaimster H, et al. PLoS One. 2014 Apr 2;9(4):e93168. doi: 10.1371/journal.pone.0093168. eCollection 2014. PLoS One. 2014. PMID: 24695245 Free PMC article.
Indole has diverse signalling roles, including modulation of biofilm formation, virulence and stress responses. ...We provide evidence that the pertinent signal in this case is not 1 mM indole in the culture supernatant but a transient pulse of intra-cellular ind …
Indole has diverse signalling roles, including modulation of biofilm formation, virulence and stress responses. ...We provide evidenc …
Antiproliferative Effect of Indole Phytoalexins.
Chripkova M, Zigo F, Mojzis J. Chripkova M, et al. Molecules. 2016 Nov 26;21(12):1626. doi: 10.3390/molecules21121626. Molecules. 2016. PMID: 27898039 Free PMC article. Review.
Indole phytoalexins from crucifers have been shown to exhibit significant anti-cancer, chemopreventive, and antiproliferative activity. ...Isolation from cruciferous plants does not provide sufficient quantities of indole phytoalexins and, for biological screening, …
Indole phytoalexins from crucifers have been shown to exhibit significant anti-cancer, chemopreventive, and antiproliferative activit …
A new prenylated indole diketopiperazine alkaloid from Eurotium cristatum.
Zou X, Li Y, Zhang X, Li Q, Liu X, Huang Y, Tang T, Zheng S, Wang W, Tang J. Zou X, et al. Molecules. 2014 Nov 3;19(11):17839-47. doi: 10.3390/molecules191117839. Molecules. 2014. PMID: 25372398 Free PMC article.
A new prenylated indole diketopiperazine alkaloid, cristatumin F (1), and four known metabolites, echinulin (2), dehydroechinulin (3), neoechinulin A (4) and variecolorin O (5), were isolated from the crude extract of the fungus Eurotium cristatum. ...
A new prenylated indole diketopiperazine alkaloid, cristatumin F (1), and four known metabolites, echinulin (2), dehydroechinulin (3) …
Total Synthesis of (-)-Alstofolinine A through a Furan Oxidation/Rearrangement and Indole Nucleophilic Cyclization Cascade.
Zhang L, Zhang Y, Li W, Qi X. Zhang L, et al. Angew Chem Int Ed Engl. 2019 Apr 1;58(15):4988-4991. doi: 10.1002/anie.201900156. Epub 2019 Mar 6. Angew Chem Int Ed Engl. 2019. PMID: 30775835
A reaction cascade of aza-Achmatowicz rearrangement followed by indole nucleophilic cyclization was developed to generate the common indole-fused azabicyclo[3.3.1]nonane core of the macroline family alkaloids. ...
A reaction cascade of aza-Achmatowicz rearrangement followed by indole nucleophilic cyclization was developed to generate the common …
Anticancer Indole-Based Chalcones: A Structural and Theoretical Analysis.
Badria FA, Soliman SM, Atef S, Islam MS, Al-Majid AM, Dege N, Ghabbour HA, Ali M, El-Senduny FF, Barakat A. Badria FA, et al. Molecules. 2019 Oct 16;24(20):3728. doi: 10.3390/molecules24203728. Molecules. 2019. PMID: 31623155 Free PMC article.
The crystal structures of five new chalcones derived from N-ethyl-3-acetylindole with different substituents were investigated: (E)-3-(4-bromophenyl)-1-(1-ethyl-1H-indol-3-yl)prop-2-en-1-one (3a); (E)-3-(3-bromophenyl)-1-(1-ethyl-1H-indol-3-yl)prop-2-en-1-one (3b); …
The crystal structures of five new chalcones derived from N-ethyl-3-acetylindole with different substituents were investigated: (E)-3-(4-bro …
Design of Synthetic Polymer Nanoparticles Specifically Capturing Indole, a Small Toxic Molecule.
Okishima A, Koide H, Hoshino Y, Egami H, Hamashima Y, Oku N, Asai T. Okishima A, et al. Biomacromolecules. 2019 Apr 8;20(4):1644-1654. doi: 10.1021/acs.biomac.8b01820. Epub 2019 Mar 15. Biomacromolecules. 2019. PMID: 30848887
Here, we describe the design of synthetic polymer nanoparticles (NPs) specifically capturing indole, a major factor exacerbating chronic kidney disease, in the intestine. ...The combination of hydrophobic and quadrupole interaction was effective to enhance the affinity and …
Here, we describe the design of synthetic polymer nanoparticles (NPs) specifically capturing indole, a major factor exacerbating chro …
366,637 results
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