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ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.
Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A. Bredow C, et al. Among authors: impens f. Cardiovasc Res. 2024 May 7;120(6):644-657. doi: 10.1093/cvr/cvae026. Cardiovasc Res. 2024. PMID: 38309955 Free PMC article.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Among authors: impens f. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
Baron L, Paatero AO, Morel JD, Impens F, Guenin-Macé L, Saint-Auret S, Blanchard N, Dillmann R, Niang F, Pellegrini S, Taunton J, Paavilainen VO, Demangel C. Baron L, et al. Among authors: impens f. J Exp Med. 2016 Dec 12;213(13):2885-2896. doi: 10.1084/jem.20160662. Epub 2016 Nov 7. J Exp Med. 2016. PMID: 27821549 Free PMC article.
Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins.
Ormancey M, Guillotin B, Merret R, Camborde L, Duboé C, Fabre B, Pouzet C, Impens F, Van Haver D, Carpentier MC, Clemente HS, Aguilar M, Lauressergues D, Scharff LB, Pichereaux C, Burlet-Schiltz O, Bousquet-Antonelli C, Gevaert K, Thuleau P, Plaza S, Combier JP. Ormancey M, et al. Among authors: impens f. Nat Commun. 2023 Jan 17;14(1):254. doi: 10.1038/s41467-023-35951-0. Nat Commun. 2023. PMID: 36650156 Free PMC article.
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis.
Van Impe K, Bethuyne J, Cool S, Impens F, Ruano-Gallego D, De Wever O, Vanloo B, Van Troys M, Lambein K, Boucherie C, Martens E, Zwaenepoel O, Hassanzadeh-Ghassabeh G, Vandekerckhove J, Gevaert K, Fernández LÁ, Sanders NN, Gettemans J. Van Impe K, et al. Among authors: impens f. Breast Cancer Res. 2013 Dec 13;15(6):R116. doi: 10.1186/bcr3585. Breast Cancer Res. 2013. PMID: 24330716 Free PMC article.
127 results