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Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Gunasekar SK, Xie L, Kumar A, Hong J, Chheda PR, Kang C, Kern DM, My-Ta C, Maurer J, Heebink J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Key P, Kulkarni CA, Beals JW, Smith GI, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Klein S, Brohawn SG, Kerns R, Sah R. Gunasekar SK, et al. Among authors: imai y. Nat Commun. 2022 Feb 10;13(1):784. doi: 10.1038/s41467-022-28435-0. Nat Commun. 2022. PMID: 35145074 Free PMC article.
Production and function of IL-12 in islets and beta cells.
Taylor-Fishwick DA, Weaver JR, Grzesik W, Chakrabarti S, Green-Mitchell S, Imai Y, Kuhn N, Nadler JL. Taylor-Fishwick DA, et al. Among authors: imai y. Diabetologia. 2013 Jan;56(1):126-35. doi: 10.1007/s00125-012-2732-9. Epub 2012 Oct 3. Diabetologia. 2013. PMID: 23052055 Free PMC article.
Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice.
Gaddam RR, Kim YR, Li Q, Jacobs JS, Gabani M, Mishra A, Promes JA, Imai Y, Irani K, Vikram A. Gaddam RR, et al. Among authors: imai y. Biochem Biophys Res Commun. 2020 Nov 5;532(2):167-172. doi: 10.1016/j.bbrc.2020.08.077. Epub 2020 Sep 17. Biochem Biophys Res Commun. 2020. PMID: 32950230 Free PMC article.
Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Mishra A, Liu S, Promes J, Harata M, Sivitz W, Fink B, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens S, King T, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum J, Imai Y. Mishra A, et al. Among authors: imai y. JCI Insight. 2021 May 10;6(9):e144341. doi: 10.1172/jci.insight.144341. JCI Insight. 2021. PMID: 33784258 Free PMC article.
4,546 results