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NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E. Allouche J, et al. Among authors: iliopoulos o. Cell. 2021 Aug 5;184(16):4268-4283.e20. doi: 10.1016/j.cell.2021.06.022. Epub 2021 Jul 6. Cell. 2021. PMID: 34233163 Free PMC article.
HIF2a inhibitors for the treatment of VHL disease.
Metelo AM, Noonan H, Iliopoulos O. Metelo AM, et al. Among authors: iliopoulos o. Oncotarget. 2015 Sep 15;6(27):23036-7. doi: 10.18632/oncotarget.4564. Oncotarget. 2015. PMID: 26325097 Free PMC article. Review. No abstract available.
Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.
Black JC, Atabakhsh E, Kim J, Biette KM, Van Rechem C, Ladd B, Burrowes PD, Donado C, Mattoo H, Kleinstiver BP, Song B, Andriani G, Joung JK, Iliopoulos O, Montagna C, Pillai S, Getz G, Whetstine JR. Black JC, et al. Among authors: iliopoulos o. Genes Dev. 2015 May 15;29(10):1018-31. doi: 10.1101/gad.259796.115. Genes Dev. 2015. PMID: 25995187 Free PMC article.
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. Zhong L, et al. Among authors: iliopoulos o. Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041. Cell. 2010. PMID: 20141841 Free PMC article.
70 results