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Page 1
L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab.
Marrocco I, Giri S, Simoni-Nieves A, Gupta N, Rudnitsky A, Haga Y, Romaniello D, Sekar A, Zerbib M, Oren R, Lindzen M, Fard D, Tsutsumi Y, Lauriola M, Tamagnone L, Yarden Y. Marrocco I, et al. Cell Rep Med. 2023 Aug 15;4(8):101142. doi: 10.1016/j.xcrm.2023.101142. Epub 2023 Aug 8. Cell Rep Med. 2023. PMID: 37557179 Free PMC article.
Tolerogenic IL-10-engineered dendritic cell-based therapy to restore antigen-specific tolerance in T cell mediated diseases.
Passeri L, Andolfi G, Bassi V, Russo F, Giacomini G, Laudisa C, Marrocco I, Cesana L, Di Stefano M, Fanti L, Sgaramella P, Vitale S, Ziparo C, Auricchio R, Barera G, Di Nardo G, Troncone R, Gianfrani C, Annoni A, Passerini L, Gregori S. Passeri L, et al. Among authors: marrocco i. J Autoimmun. 2023 Jul;138:103051. doi: 10.1016/j.jaut.2023.103051. Epub 2023 May 22. J Autoimmun. 2023. PMID: 37224733 Free article.
ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity.
Di Risola D, Ricci D, Marrocco I, Giamogante F, Grieco M, Francioso A, Vasco-Vidal A, Mancini P, Colotti G, Mosca L, Altieri F. Di Risola D, et al. Among authors: marrocco i. J Neurochem. 2022 Aug;162(4):322-336. doi: 10.1111/jnc.15655. Epub 2022 Jul 8. J Neurochem. 2022. PMID: 35699375 Free PMC article.
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis.
Uribe ML, Dahlhoff M, Batra RN, Nataraj NB, Haga Y, Drago-Garcia D, Marrocco I, Sekar A, Ghosh S, Vaknin I, Lebon S, Kramarski L, Tsutsumi Y, Choi I, Rueda OM, Caldas C, Yarden Y. Uribe ML, et al. Among authors: marrocco i. Sci Signal. 2021 Jun 22;14(688):eabe6156. doi: 10.1126/scisignal.abe6156. Sci Signal. 2021. PMID: 34158398 Free PMC article.
An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation.
Ricci D, Tutton S, Marrocco I, Ying M, Blumenthal D, Eletto D, Vargas J, Boyle S, Fazelinia H, Qian L, Suresh K, Taylor D, Paton JC, Paton AW, Tang CA, Hu CA, Radhakrishnan R, Gidalevitz T, Argon Y. Ricci D, et al. Among authors: marrocco i. J Biol Chem. 2021 Jan-Jun;296:100781. doi: 10.1016/j.jbc.2021.100781. Epub 2021 May 14. J Biol Chem. 2021. PMID: 34000298 Free PMC article.
Host-Dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors.
Haga Y, Marrocco I, Noronha A, Uribe ML, Nataraj NB, Sekar A, Drago-Garcia D, Borgoni S, Lindzen M, Giri S, Wiemann S, Tsutsumi Y, Yarden Y. Haga Y, et al. Among authors: marrocco i. Cancer Res. 2021 Jul 15;81(14):3862-3875. doi: 10.1158/0008-5472.CAN-20-3555. Epub 2021 May 3. Cancer Res. 2021. PMID: 33941614 Free PMC article.
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