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Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Johmura Y, et al. Among authors: ikeda k. Science. 2021 Jan 15;371(6526):265-270. doi: 10.1126/science.abb5916. Science. 2021. PMID: 33446552
Triacylglycerol/phospholipid molecular species profiling of fatty livers and regenerated non-fatty livers in cystathionine beta-synthase-deficient mice, an animal model for homocysteinemia/homocystinuria.
Ikeda K, Kubo A, Akahoshi N, Yamada H, Miura N, Hishiki T, Nagahata Y, Matsuura T, Suematsu M, Taguchi R, Ishii I. Ikeda K, et al. Anal Bioanal Chem. 2011 Jun;400(7):1853-63. doi: 10.1007/s00216-011-4703-2. Epub 2011 Feb 8. Anal Bioanal Chem. 2011. PMID: 21301820
Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer's disease.
Tajima Y, Ishikawa M, Maekawa K, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Ikeda K, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y. Tajima Y, et al. Among authors: ikeda k. Lipids Health Dis. 2013 May 9;12:68. doi: 10.1186/1476-511X-12-68. Lipids Health Dis. 2013. PMID: 23659495 Free PMC article.
Reconstruction of insulin signal flow from phosphoproteome and metabolome data.
Yugi K, Kubota H, Toyoshima Y, Noguchi R, Kawata K, Komori Y, Uda S, Kunida K, Tomizawa Y, Funato Y, Miki H, Matsumoto M, Nakayama KI, Kashikura K, Endo K, Ikeda K, Soga T, Kuroda S. Yugi K, et al. Among authors: ikeda k. Cell Rep. 2014 Aug 21;8(4):1171-83. doi: 10.1016/j.celrep.2014.07.021. Epub 2014 Aug 14. Cell Rep. 2014. PMID: 25131207 Free article.
Reduction of lipid accumulation rescues Bietti's crystalline dystrophy phenotypes.
Hata M, Ikeda HO, Iwai S, Iida Y, Gotoh N, Asaka I, Ikeda K, Isobe Y, Hori A, Nakagawa S, Yamato S, Arita M, Yoshimura N, Tsujikawa A. Hata M, et al. Among authors: ikeda k, ikeda ho. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3936-3941. doi: 10.1073/pnas.1717338115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581279 Free PMC article.
Reelin deficiency leads to aberrant lipid composition in mouse brain.
Mizukami T, Ikeda K, Shimanaka Y, Korogi K, Zhou C, Takase H, Tsuiji H, Kono N, Kohno T, Arai H, Arita M, Hattori M. Mizukami T, et al. Among authors: ikeda k. Biochem Biophys Res Commun. 2018 Oct 20;505(1):81-86. doi: 10.1016/j.bbrc.2018.09.089. Epub 2018 Sep 18. Biochem Biophys Res Commun. 2018. PMID: 30241938
7,100 results