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SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.
Hashimoto R, Takahashi J, Shirakura K, Funatsu R, Kosugi K, Deguchi S, Yamamoto M, Tsunoda Y, Morita M, Muraoka K, Tanaka M, Kanbara T, Tanaka S, Tamiya S, Tokunoh N, Kawai A, Ikawa M, Ono C, Tachibana K, Kondoh M, Obana M, Matsuura Y, Ohsumi A, Noda T, Yamamoto T, Yoshioka Y, Torisawa YS, Date H, Fujio Y, Nagao M, Takayama K, Okada Y. Hashimoto R, et al. Among authors: ikawa m. Sci Adv. 2022 Sep 23;8(38):eabo6783. doi: 10.1126/sciadv.abo6783. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129989 Free PMC article.
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.
Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, Hashimoto R, Shigesada N, Takahashi J, Tachibana M, Tanaka S, Obana M, Hino N, Ikawa M, Tsujikawa K, Ono C, Matsuura Y, Kidoya H, Takakura N, Kubota Y, Doi T, Takayama K, Yoshioka Y, Fujio Y, Okada Y. Morita M, et al. Among authors: ikawa m. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2213317120. doi: 10.1073/pnas.2213317120. Epub 2023 Jan 12. Proc Natl Acad Sci U S A. 2023. PMID: 36634143 Free PMC article.
Infection with flaviviruses requires BCLXL for cell survival.
Suzuki T, Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S, Matsuura Y. Suzuki T, et al. Among authors: ikawa m. PLoS Pathog. 2018 Sep 27;14(9):e1007299. doi: 10.1371/journal.ppat.1007299. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30261081 Free PMC article.
USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation.
Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, Hirano J, Zhang H, Chen DV, Ishiga H, Komoda Y, Ono C, Fukuhara T, Yamamoto M, Ikawa M, Satoh T, Akira S, Tanaka T, Moriishi K, Fukai M, Taketomi A, Yoshio S, Kanto T, Suzuki T, Okamoto T, Matsuura Y. Kusakabe S, et al. Among authors: ikawa m. J Virol. 2019 Mar 5;93(6):e01708-18. doi: 10.1128/JVI.01708-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30626683 Free PMC article.
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.
Akamine T, Terabayashi T, Sasaki T, Hayashi R, Abe I, Hirayama F, Nureki SI, Ikawa M, Miyata H, Tokunaga A, Kobayashi T, Hanada K, Thumkeo D, Narumiya S, Ishizaki T. Akamine T, et al. Among authors: ikawa m. FEBS Open Bio. 2024 Apr 11. doi: 10.1002/2211-5463.13802. Online ahead of print. FEBS Open Bio. 2024. PMID: 38604990 Free article.
576 results