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Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Among authors: ignatova z. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
smORFer: a modular algorithm to detect small ORFs in prokaryotes.
Bartholomäus A, Kolte B, Mustafayeva A, Goebel I, Fuchs S, Benndorf D, Engelmann S, Ignatova Z. Bartholomäus A, et al. Among authors: ignatova z. Nucleic Acids Res. 2021 Sep 7;49(15):e89. doi: 10.1093/nar/gkab477. Nucleic Acids Res. 2021. PMID: 34125903 Free PMC article.
In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence.
Ignatova Z, Thakur AK, Wetzel R, Gierasch LM. Ignatova Z, et al. J Biol Chem. 2007 Dec 14;282(50):36736-43. doi: 10.1074/jbc.M703682200. Epub 2007 Oct 17. J Biol Chem. 2007. PMID: 17942400 Free PMC article.
Previously we showed that fusion of the huntingtin exon 1 sequence with >40Q led to structural perturbation and decreased stability of CRABP (Ignatova, Z., and Gierasch, L. M. (2006) J. Biol. Chem. 281, 12959-12967). ...
Previously we showed that fusion of the huntingtin exon 1 sequence with >40Q led to structural perturbation and decreased stability of CR …
125 results